De Castro M F, Schenberg L C
Departamento de Ciências Fisiológicas, Universidade Federal do Espírito Santo, Vitória, Brasil.
Braz J Med Biol Res. 1989;22(1):115-9.
The mean blood pressure and heart rate of freely moving rats were directly recorded over a 1-min period of electrical stimulation of the periaqueductal gray with intensities that induced freezing behavior, intense flight or no behavioral changes. Blood pressure and heart rate increased only when flight was induced and only during the first 15 s of stimulation. These cardiovascular changes suggest that homeostatic mechanisms act during the defense reaction and are markedly inhibited only at the beginning of the stimuli that induce the flight response, this inhibition quickly undergoing attenuation. These data do not suggest that activation of defense area, per se, contributes to the development of primary hypertension.
在自由活动的大鼠中，通过电刺激导水管周围灰质，以能诱发僵住行为、强烈逃跑反应或无行为变化的强度，直接记录1分钟内的平均血压和心率。只有在诱发逃跑反应时，且仅在刺激的前15秒内，血压和心率才会升高。这些心血管变化表明，稳态机制在防御反应中起作用，并且仅在诱发逃跑反应的刺激开始时受到显著抑制，这种抑制会迅速减弱。这些数据并不表明防御区域的激活本身会导致原发性高血压的发生。
