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维生素E对红细胞保存的影响。

Effect of vitamin E on red blood cell preservation.

作者信息

Leonart M S, Weffort-Santos A M, Muñoz E M, Higuti I H, Fortes V A, Nascimento A J

机构信息

Departamento de Patologia Médica, Universidade Federal do Paraná, Curitiba, Brasil.

出版信息

Braz J Med Biol Res. 1989;22(1):85-6.

PMID:2758176
Abstract

The effect of exogenous vitamin E (2.1 mg/100 ml) was determined on the preservation of red blood cell integrity (PCV and RBC counts) during long-term storage. Cells from healthy human blood donors, normal rats and rats raised on a vitamin E-deficient diet were stored in CE medium at 4 degrees C for 40-60 days. The addition of vitamin E to the CE medium protected normal rat RBC and those from vitamin E-deficient animals to even a larger extent. Neither the PVC nor RBC count in human blood changed during storage for up to 60 days and no effect of exogenous vitamin E was demonstrable.

摘要

研究了外源性维生素E(2.1毫克/100毫升)对长期储存期间红细胞完整性(红细胞压积和红细胞计数)的保存作用。将来自健康人类献血者、正常大鼠以及以维生素E缺乏饮食饲养的大鼠的细胞,在4℃下于CE培养基中储存40 - 60天。向CE培养基中添加维生素E对正常大鼠红细胞以及维生素E缺乏动物的红细胞具有更大程度的保护作用。人类血液中的红细胞压积和红细胞计数在长达60天的储存期间均未发生变化,且未显示出外源性维生素E的作用。

相似文献

1
Effect of vitamin E on red blood cell preservation.维生素E对红细胞保存的影响。
Braz J Med Biol Res. 1989;22(1):85-6.
2
Protective effects of vitamins E and C on erythrocytes in blood preserved in ACD solution and stored at 4 degrees C.维生素E和维生素C对保存在ACD溶液中并于4℃储存的血液中红细胞的保护作用。
Haematologia (Budap). 1988;21(4):219-26.
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Transfus Med. 2017 Jun;27(3):213-217. doi: 10.1111/tme.12394. Epub 2017 Feb 23.
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Murine red blood cell fragility is not affected by either vitamin E depletion or supplementation.小鼠红细胞脆性不受维生素E缺乏或补充的影响。
Proc Soc Exp Biol Med. 1996 Jul;212(3):280-3. doi: 10.3181/00379727-212-44017.
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Filterability of erythrocytes from vitamin E-deficient lead-poisoned rats.维生素E缺乏的铅中毒大鼠红细胞的滤过性
J Nutr. 1977 Mar;107(3):363-72. doi: 10.1093/jn/107.3.363.
6
[Effect of vitamin E on the stability of erythrocytes and the practical use of this knowledge in blood preservation].[维生素E对红细胞稳定性的影响及其在血液保存中的实际应用]
Int Z Vitaminforsch. 1965;35(2):138-52.
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Lead poisoning in vitamin E-deficient rats.维生素E缺乏大鼠中的铅中毒
J Nutr. 1975 Nov;105(11):1481-5. doi: 10.1093/jn/105.11.1481.
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Effect of alpha-tocopherol administration on red cell survival in vitamin E-deficient human subjects.α-生育酚给药对维生素E缺乏的人类受试者红细胞存活的影响。
Am J Clin Nutr. 1971 Apr;24(4):388-93. doi: 10.1093/ajcn/24.4.388.
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引用本文的文献

1
Red blood cell storage lesion: causes and potential clinical consequences.红细胞储存损伤:原因及潜在临床后果。
Blood Transfus. 2019 Jan;17(1):27-52. doi: 10.2450/2019.0217-18.
2
Metabolic pathways that correlate with post-transfusion circulation of stored murine red blood cells.与储存的小鼠红细胞输血后循环相关的代谢途径。
Haematologica. 2016 May;101(5):578-86. doi: 10.3324/haematol.2015.139139. Epub 2016 Feb 26.