Lee Pow Crystal S D, Law J Mac, Kwak Thomas J, Cope W Gregory, Rice James A, Kullman Seth W, Aday D Derek
Department of Biological Sciences, Environmental and Molecular Toxicology Program, North Carolina State University, Raleigh, North Carolina, USA.
Department of Population Health and Pathobiology, North Carolina State University, Raleigh, North Carolina, USA.
Environ Toxicol Chem. 2017 Apr;36(4):959-968. doi: 10.1002/etc.3607. Epub 2016 Oct 20.
Male fish are susceptible to developing intersex, a condition characterized by the presence of testicular oocytes. In the present study, the relationship between intersex and exposure to estrogenic endocrine active contaminants (EACs) was assessed for 2 genera of sport fish, Micropterus and Lepomis, at 20 riverine sites. Seasonal trends and relationships between EACs and intersex (prevalence and severity) were examined at varying putative sources of EACs throughout North Carolina, identified as point sources, nonpoint sources, and reference sites. Intersex was identified in both genera, which was documented for the first time in wild-caught Lepomis. Intersex was more prevalent (59.8%) and more severe (1.6 mean rank) in Micropterus, which was highly correlation to EACs in sediment. In contrast, intersex was less common (9.9%) and less severe (0.2 mean rank) in Lepomis and was highly correlated to EACs in the water column. The authors found that concentrations of polycyclic aromatic hydrocarbons, polychlorinated biphenyls, industrial EACs, and estrogens were highest at point source sites; however, no source type variation was identified in the prevalence or severity of intersex, nor were there seasonal trends in intersex or EAC concentrations. The authors' results associate genus-specific prevalence of intersex with specific EAC classes in common sport fishes having biological, ecological, and conservation implications. Environ Toxicol Chem 2017;36:959-968. © 2016 SETAC.
雄鱼易患雌雄同体症，其特征为出现睾丸卵母细胞。在本研究中，针对20个河滨地点的2种游钓鱼类（小口黑鲈属和太阳鱼属），评估了雌雄同体症与暴露于雌激素类内分泌活性污染物（EACs）之间的关系。在北卡罗来纳州不同的假定EACs来源处（确定为点源、非点源和参考地点），研究了EACs与雌雄同体症（患病率和严重程度）之间的季节性趋势及关系。在这两个属中均发现了雌雄同体现象，这在野生捕获的太阳鱼属中尚属首次记录。雌雄同体症在小口黑鲈属中更为普遍（59.8%）且更为严重（平均秩为1.6），这与沉积物中的EACs高度相关。相比之下，雌雄同体症在太阳鱼属中较不常见（9.9%）且不太严重（平均秩为0.2），并且与水柱中的EACs高度相关。作者发现多环芳烃、多氯联苯、工业EACs和雌激素的浓度在点源地点最高；然而，在雌雄同体症的患病率或严重程度方面未发现源类型差异，雌雄同体症或EACs浓度也没有季节性趋势。作者的研究结果表明，常见游钓鱼类中雌雄同体症的属特异性患病率与特定的EAC类别相关，具有生物学、生态学和保护意义。《环境毒理学与化学》2017年；36：959 - 968。© 2016 SETAC。
