Svobodová J, Becvár R, Novotná J, Havelka S, Adam M
Cesk Pediatr. 1989 Jun;44(6):334-6.
Using the ELISA method, the authors assessed titres of antibodies to collagen type I, II and III in serum of patients with juvenile chronic arthritis (JCA). The results were compared with antibody titres in patients with rheumatoid arthritis (RA). Elevated antibody titres to all collagen types were found, as compared with age-matched controls. The mean titres in patients with RA were higher than in the group with JCA. Investigation of a correlation between the collagen antibody titres and values of the sedimentation rate after one hour revealed a statistical relationship only in collagen type II in patients with RA.
作者采用酶联免疫吸附测定（ELISA）法评估青少年慢性关节炎（JCA）患者血清中抗I型、II型和III型胶原蛋白的抗体滴度。将结果与类风湿性关节炎（RA）患者的抗体滴度进行比较。与年龄匹配的对照组相比，发现所有胶原蛋白类型的抗体滴度均升高。RA患者的平均滴度高于JCA组。对RA患者胶原蛋白抗体滴度与一小时后血沉值之间的相关性进行研究，结果显示仅在II型胶原蛋白方面存在统计学关系。
