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系统性红斑狼疮中的偶然分枝杆菌

Mycobacterium fortuitum in systemic lupus erythematosus.

作者信息

Laborde H, Rodrigue S, Catoggio P M

机构信息

6th Department of Internal Medicine, University Hospital, Buenos Aires, Argentina.

出版信息

Clin Exp Rheumatol. 1989 May-Jun;7(3):291-3.

PMID:2758709
Abstract

When she was five years old, this patient - aged 20 time of death - had had two diagnoses: Leri-Weill's disease and SLE. The latter led to uninterrupted use of systemic corticosteroids. Twelve months before death, multiple purulent bursitis were followed by cutaneous nodules. From the latter, but not from the former, Mycobacterium fortuitum was isolated. Our case is in agreement with what is generally accepted: this saprophyte organism becomes pathogenic in disseminated infections, only if the immune system deteriorates.

摘要

该患者死亡时20岁,5岁时曾被诊断出患有两种疾病:莱里-韦尔病和系统性红斑狼疮(SLE)。后者导致患者持续使用全身性皮质类固醇。在死亡前12个月,患者先是出现多发性脓性滑囊炎,随后出现皮肤结节。从皮肤结节中分离出偶然分枝杆菌,而脓性滑囊炎中未分离出。我们的病例与普遍认知相符:只有在免疫系统恶化时,这种腐生生物才会在播散性感染中致病。

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