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妊娠系统性红斑狼疮(SLE)患者合并非结核分枝杆菌菌血症:病例回顾及汇总病例分析。

Non-tuberculous mycobacterium bacteraemia in a pregnant systemic lupus erythematosus (SLE) patient: a case review and pooled case analysis.

机构信息

Department of Medicine, Universiti Kebangsaan Malaysia Medical Centre, 56000, Kuala Lumpur, Malaysia.

Department of Medicine, University Putra Malaysia, 43400, Serdang, Malaysia.

出版信息

Clin Rheumatol. 2018 Mar;37(3):837-847. doi: 10.1007/s10067-017-3855-7. Epub 2017 Oct 3.

Abstract

Non-tuberculous mycobacteria (NTM) are recognized as an important cause of human diseases and infections. It is commonly known to cause infections of the skin, soft tissue infections, and pulmonary infection as well as bacteraemia. We report a challenging case of severe mycobacterium abscessus bacteraemia in a pregnant lady with active systemic lupus erythematous (SLE). A comprehensive literature review of NTM infection among SLE patients was also performed, and pooled analysis of the reported cases, including our case, was done to determine the clinical characteristics and factors associated with poor outcome of NTM infection.

摘要

非结核分枝杆菌(NTM)被认为是人类疾病和感染的重要原因。它通常可引起皮肤感染、软组织感染和肺部感染以及菌血症。我们报告了一例患有活动系统性红斑狼疮(SLE)的孕妇中严重的脓肿分枝杆菌菌血症的挑战性病例。还对 SLE 患者的 NTM 感染进行了全面的文献回顾,并对包括我们的病例在内的报告病例进行了汇总分析,以确定 NTM 感染不良结局的相关临床特征和因素。

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