Smith T O, Aboelmagd T, Hing C B, MacGregor A
University of East Anglia, Norwich, UK.
Norfolk and Norwich University Hospital, Norwich, UK.
Bone Joint J. 2016 Sep;98-B(9):1160-6. doi: 10.1302/0301-620X.98B9.38024.
AIMS: Our aim was to determine whether, based on the current literature, bariatric surgery prior to total hip (THA) or total knee arthroplasty (TKA) reduces the complication rates and improves the outcome following arthroplasty in obese patients. METHODS: A systematic literature search was undertaken of published and unpublished databases on the 5 November 2015. All papers reporting studies comparing obese patients who had undergone bariatric surgery prior to arthroplasty, or not, were included. Each study was assessed using the Downs and Black appraisal tool. A meta-analysis of risk ratios (RR) and 95% confidence intervals (CI) was performed to determine the incidence of complications including wound infection, deep vein thrombosis (DVT), pulmonary embolism (PE), revision surgery and mortality. RESULTS: From 156 potential studies, five were considered to be eligible for inclusion in the study. A total of 23 348 patients (657 who had undergone bariatric surgery, 22 691 who had not) were analysed. The evidence-base was moderate in quality. There was no statistically significant difference in outcomes such as superficial wound infection (relative risk (RR) 1.88; 95% confidence interval (CI) 0.95 to 0.37), deep wound infection (RR 1.04; 95% CI 0.65 to 1.66), DVT (RR 0.57; 95% CI 0.13 to 2.44), PE (RR 0.51; 95% CI 0.03 to 8.26), revision surgery (RR 1.24; 95% CI 0.75 to 2.05) or mortality (RR 1.25; 95% CI 0.16 to 9.89) between the two groups. CONCLUSION: For most peri-operative outcomes, bariatric surgery prior to THA or TKA does not significantly reduce the complication rates or improve the clinical outcome. This study questions the previous belief that bariatric surgery prior to arthroplasty may improve the clinical outcomes for patients who are obese or morbidly obese. This finding is based on moderate quality evidence. Cite this article: Bone Joint J 2016;98-B:1160-6.
目的:我们的目的是根据当前文献,确定在全髋关节置换术(THA)或全膝关节置换术(TKA)之前进行减肥手术是否能降低肥胖患者关节置换术后的并发症发生率并改善预后。 方法:于2015年11月5日对已发表和未发表的数据库进行了系统的文献检索。纳入所有报告比较了在关节置换术前接受或未接受减肥手术的肥胖患者的研究。每项研究都使用唐斯和布莱克评估工具进行评估。对风险比(RR)和95%置信区间(CI)进行荟萃分析,以确定包括伤口感染、深静脉血栓形成(DVT)、肺栓塞(PE)、翻修手术和死亡率在内的并发症发生率。 结果:从156项潜在研究中,有5项被认为符合纳入该研究的条件。共分析了23348例患者(657例接受了减肥手术,22691例未接受)。证据质量中等。两组在浅表伤口感染(相对风险(RR)1.88;95%置信区间(CI)0.95至3.7)、深部伤口感染(RR 1.04;95% CI 0.65至1.66)、DVT(RR 0.57;95% CI 0.13至2.44)、PE(RR 0.51;95% CI 0.03至8.26)、翻修手术(RR 1.24;95% CI 0.75至2.05)或死亡率(RR 1.25;95% CI 0.16至9.89)等结果方面没有统计学上的显著差异。 结论:对于大多数围手术期结果,THA或TKA之前的减肥手术并不能显著降低并发症发生率或改善临床结果。本研究对先前认为关节置换术前进行减肥手术可能改善肥胖或病态肥胖患者临床结果的观点提出了质疑。这一发现基于中等质量的证据。引用本文:《骨与关节杂志》2016年;98 - B:1160 - 6。
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