Shen Deqiang, Bai Hao, Li Zhaoping, Yu Yue, Zhang Huanhuan, Chen Liyong
a Department of Nutrition and Food Hygiene , School of Public health, Shandong University , Jinan , China.
b Department of Nutrition , Shandong Provincial Hospital Affiliated to Shandong University , Jinan , China.
Int J Food Sci Nutr. 2017 Mar;68(2):149-157. doi: 10.1080/09637486.2016.1226275. Epub 2016 Sep 4.
Animal experimental studies have found that resistant starch can significantly improve bowel function, but the outcomes are mixed while conducting human studies. Thus, we conducted a systematic review and meta-analysis of randomized controlled trials to evaluate the relationship between resistant starch supplementation and large intestinal function. Three electronic databases (PubMed, Embase, Scopus) were searched to identify eligible studies. The standardized mean difference (SMD) or weighted mean difference (WMD) was calculated using a fixed-effects model or a random-effects model. The pooled findings revealed that resistant starch significantly increased fecal wet weight (WMD 35.51 g/d, 95% CI 1.21, 69.82) and butyrate concentration (SMD 0.61, 95% CI 0.32, 0.89). Also, it significantly reduced fecal PH (WMD -0.19, 95% CI -0.35, -0.03), but the increment of defecation frequency were not statistically significant (WMD 0.04stools/g, 95% CI -0.08, 0.16). To conclude, our study found that resistant starch elicited a beneficial effect on the function of large bowel in healthy adults.[Formula: see text].
动物实验研究发现，抗性淀粉可显著改善肠道功能，但在人体研究中的结果却参差不齐。因此，我们对随机对照试验进行了系统评价和荟萃分析，以评估补充抗性淀粉与大肠功能之间的关系。通过检索三个电子数据库（PubMed、Embase、Scopus）来确定符合条件的研究。使用固定效应模型或随机效应模型计算标准化均数差（SMD）或加权均数差（WMD）。汇总结果显示，抗性淀粉显著增加了粪便湿重（WMD 35.51 g/d，95%CI 1.21，69.82）和丁酸盐浓度（SMD 0.61，95%CI 0.32，0.89）。此外，它还显著降低了粪便pH值（WMD -0.19，95%CI -0.35，-0.03），但排便频率的增加无统计学意义（WMD 0.04次/克，95%CI -0.08，0.16）。总之，我们的研究发现抗性淀粉对健康成年人的大肠功能有有益影响。[公式：见正文]
