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遗传性胎儿血红蛋白持续存在的患者因细胞减少症和巨大的脊柱旁肿块导致脊髓压迫而出现髓外造血。

Extramedullary hematopoiesis presented as cytopenia and massive paraspinal masses leading to cord compression in a patient with hereditary persistence of fetal hemoglobin.

机构信息

Division of Hematology and Oncology, New York Medical College and Westchester Medical Center, Valhalla, NY 10595 USA.

出版信息

Biomark Res. 2016 Sep 1;4(1):17. doi: 10.1186/s40364-016-0071-6. eCollection 2016.

DOI:10.1186/s40364-016-0071-6
PMID:27595000
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5009637/
Abstract

BACKGROUND

Extramedullary hematopoeisis (EMH) can occur in various physiological and pathologic states. The spleen is the most common site of EMH.

CASE PRESENTATION

We report a case with hereditary persistence of fetal hemoglobin with extramedullary hematopoiesis presented as cord compression and cytopenia secondary to multi-paraspinal masses.

CONCLUSION

Treatment can be a challenge. Relapse is a possibility.

摘要

背景

骨髓外造血（EMH）可发生于各种生理和病理状态。脾脏是 EMH 最常见的部位。

病例介绍

我们报告了一例遗传性胎儿血红蛋白持续存在病例，其表现为因多发脊柱旁肿块导致的脐带压迫和血细胞减少。

结论

治疗可能具有挑战性。复发是一种可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4710/5009637/5dc7aab24e11/40364_2016_71_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4710/5009637/582f192ea441/40364_2016_71_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4710/5009637/5dc7aab24e11/40364_2016_71_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4710/5009637/582f192ea441/40364_2016_71_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4710/5009637/5dc7aab24e11/40364_2016_71_Fig2_HTML.jpg

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