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高脂饮食对种植体骨结合的影响:一项实验研究。

The effects of high-fat diet on implant osseointegration: an experimental study.

作者信息

Dündar Serkan, Yaman Ferhan, Ozupek Muhammed Fatih, Saybak Arif, Gul Mehmet, Asutay Fatih, Kirtay Mustafa, Ozercan Ibrahim Hanifi

机构信息

Department of Periodontology, Faculty of Dentistry, Firat University, Elazig, Turkey.

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Dicle University, Diyarbakir, Turkey.

出版信息

J Korean Assoc Oral Maxillofac Surg. 2016 Aug;42(4):187-92. doi: 10.5125/jkaoms.2016.42.4.187. Epub 2016 Aug 24.

DOI:10.5125/jkaoms.2016.42.4.187
PMID:27595085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5009192/
Abstract

OBJECTIVES

In this study, we investigated whether a high-fat diet (HFD) affected the bone implant connection (BIC) in peri-implant bone.

MATERIALS AND METHODS

Four male rabbits were used in this study. Dental implant surgery was introduced into each tibia, and four implants were integrated into each animal. In both the normal diet (ND) group (n=2) and HFD group (n=2), 8 implants were integrated, for a total of 16 integrated implants. The animals continued with their respective diets for 12 weeks post-surgery. Afterward, the rabbits were sacrificed, and the BIC was assessed histomorphometrically.

RESULTS

Histologic and histomorphometric analyses demonstrated that BIC was not impaired in the HFD group compared to the ND group.

CONCLUSION

Within the limitations of this study, we found that HFD did not decrease the BIC in rabbit tibias.

摘要

目的

在本研究中,我们调查了高脂饮食(HFD)是否会影响种植体周围骨中的骨种植体连接(BIC)。

材料与方法

本研究使用了4只雄性兔子。在每只兔子的胫骨上进行牙种植手术,每只动物植入4枚种植体。正常饮食(ND)组(n = 2)和高脂饮食(HFD)组(n = 2)均植入8枚种植体,共16枚植入的种植体。术后,动物继续各自的饮食12周。之后,处死兔子,通过组织形态计量学评估骨种植体连接。

结果

组织学和组织形态计量学分析表明,与ND组相比,HFD组的骨种植体连接未受损。

结论

在本研究的局限性范围内,我们发现高脂饮食不会降低兔胫骨中的骨种植体连接。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/310a/5009192/783b5c7815fa/jkaoms-42-187-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/310a/5009192/783b5c7815fa/jkaoms-42-187-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/310a/5009192/783b5c7815fa/jkaoms-42-187-g001.jpg

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High-fructose and high-fat diet-induced insulin resistance enhances atherosclerosis in Watanabe heritable hyperlipidemic rabbits.高果糖高脂肪饮食诱导的胰岛素抵抗会加剧渡边遗传性高脂血症兔的动脉粥样硬化。
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