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[低热量蛋白质 - 碳水化合物饮食住院减重4年后严重超重青少年的随访研究]

[Follow-up study of severely overweight adolescents 4 years following inpatient weight loss with a low calorie protein-carbohydrate diet].

作者信息

Nanoff C, Zwiauer K, Widhalm K

机构信息

Universitäts-Kinderklinik Wien.

出版信息

Infusionstherapie. 1989 Jun;16(3):141-4.

PMID:2759710
Abstract

Very low calorie protein/carbohydrate diets have proved to be efficient and safe in the treatment of obesity in childhood and early adolescence. The follow-up study at issue shows that subsequent to short-term therapy no further reduction in weight is to be expected without adequate care following the diet. Between 1980 and 1983, 27 adolescent patients were treated for severe obesity (78.12% +/- 18.3% overweight, mean +/- s.e.m.) at the metabolic ward of the department of pediatrics, University of Vienna. The administration of a very low calorie protein/carbohydrate diet (VLCD) for 26 (+/- 7) days led to a considerable reduction in overweight (8.1 +/- 2.9 kg). On dismission the percentual overweight had decreased to 59.4 (+/- 24)%. After 4.4 (+/- 0.7) years the weight of 11 of the 27 patients could be controlled, 10 patients refused further cooperation and the remaining 6 could not be addressed. The body mass index (weight/height) had risen from 29.4 (+/- 1.2) to 43.0 (+/- 6.0) with 10 of 11 patients, corresponding to a percentual overweight of 88.2 (+/- 18.1)% at the follow-up date. Only one girl had reduced overweight by 45%, the BMI had fallen from 33.9 to 27.1. Furthermore, our data suggest that obesity induces a significant increase in blood pressure in adolescents. This rise is apparently independent of the age related increase in blood pressure and revertible by weight loss. The results we have to hand show that long-term weight reduction has only been achieved in 1 of 11 cases, with none of the adolescents having participated regularly in an outpatient after-care program.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

极低热量蛋白质/碳水化合物饮食已被证明在治疗儿童期和青春期早期肥胖方面有效且安全。该问题的随访研究表明,短期治疗后,如果饮食后没有适当护理,体重不会进一步减轻。1980年至1983年期间,维也纳大学儿科代谢病房对27名青少年严重肥胖患者进行了治疗(超重78.12%±18.3%,平均±标准误)。给予极低热量蛋白质/碳水化合物饮食(VLCD)26(±7)天导致超重显著减轻(8.1±2.9千克)。出院时超重百分比降至59.4(±24)%。4.4(±0.7)年后,27名患者中有11名体重得到控制,10名患者拒绝进一步合作,其余6名无法联系上。11名患者中有10名的体重指数(体重/身高)从29.4(±1.2)升至43.0(±6.0),随访时超重百分比为88.2(±18.1)%。只有一名女孩超重减轻了45%,体重指数从33.9降至27.1。此外,我们的数据表明肥胖会导致青少年血压显著升高。这种升高显然与年龄相关的血压升高无关,且可通过减肥恢复。我们现有的结果表明,11例中只有1例实现了长期体重减轻,没有青少年定期参加门诊后续护理项目。(摘要截断于250字)

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