Sharma Vibhor, Dora Tapas, Patel Mehul, Sancheti Sankalp, Sridhar Epari
Department of Medical Oncology, Homi Bhabha Cancer Hospital, Sangrur, Punjab 148001, India.
Department of Radiotherapy, Homi Bhabha Cancer Hospital, Sangrur, Punjab 148001, India.
Case Rep Hematol. 2016;2016:3042531. doi: 10.1155/2016/3042531. Epub 2016 Aug 11.
Lymphoma of the uterine cervix is very rare. We report a case of diffuse large B cell lymphoma (DLBCL) involving the uterine cervix treated at a newly commissioned semiurban cancer centre in north India in 2015. Data for this study was obtained from the hospital electronic medical records and the patient's case file. We also reviewed published case reports of uterine and cervical lymphoma involving forty-one patients. We treated a case of stage IV DLBCL cervix with six cycles of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone) and intrathecal methotrexate followed by consolidation with radiotherapy. The patient showed complete response to chemotherapy. We conclude that, in advanced stage lymphoma involving uterus and cervix, combination of chemotherapy and radiotherapy is effective in short term.
子宫颈淋巴瘤非常罕见。我们报告一例2015年在印度北部一家新启用的半城市癌症中心接受治疗的累及子宫颈的弥漫性大B细胞淋巴瘤（DLBCL）。本研究的数据来自医院电子病历和患者病历档案。我们还回顾了已发表的涉及41例患者的子宫和宫颈淋巴瘤病例报告。我们用六个周期的R-CHOP（利妥昔单抗、环磷酰胺、多柔比星、长春新碱和泼尼松龙）和鞘内注射甲氨蝶呤治疗了一例IV期子宫颈DLBCL患者，随后进行放疗巩固治疗。患者对化疗表现出完全缓解。我们得出结论，在累及子宫和宫颈的晚期淋巴瘤中，化疗和放疗联合在短期内是有效的。
