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同步原发性子宫内膜癌和双侧卵巢癌的皮肤转移:一种罕见的表现及文献综述

Cutaneous Metastases of the Synchronous Primary Endometrial and Bilateral Ovarian Cancer: An Infrequent Presentation and Literature Review.

作者信息

Kanyilmaz Gul, Aktan Meryem, Koc Mehmet, Findik Siddika

机构信息

Department of Radiation Oncology, Meram Medicine School, Necmettin Erbakan University, Akyokus Mevkii, 42090 Konya, Turkey.

Department of Pathology, Meram Medicine School, Necmettin Erbakan University, Akyokus Mevkii, 42090 Konya, Turkey.

出版信息

Case Rep Oncol Med. 2016;2016:4568653. doi: 10.1155/2016/4568653. Epub 2016 Aug 11.

Abstract

There are limited data about the cutaneous metastases of gynecological malignancies in the literature. Based on this limited number of studies, cutaneous metastases from gynecological malignancies are uncommon occurrences. Cutaneous metastases from the synchronous endometrioid carcinoma of the uterine corpus and bilateral ovaries arising from endometriosis are extremely rare. Herein, we report a 51-year-old woman with FIGO Stage 1A Grade 1 endometrial endometrioid-type adenocarcinoma and synchronous bilateral Stage 1B ovarian endometrioid-type adenocarcinoma who presented 34 months following total abdominal hysterectomy and bilateral salpingo-oophorectomy with skin metastases. After the patient underwent an excisional biopsy, we applied a palliative radiotherapy. The patient received the combination therapy with cisplatin and doxorubicin after the completion of radiotherapy but the disease evolution was rapidly fatal and the patient died 4 months after her admission to our department due to widely disseminated disease.

摘要

关于妇科恶性肿瘤皮肤转移的文献资料有限。基于这少量的研究,妇科恶性肿瘤的皮肤转移并不常见。子宫体同步子宫内膜样癌和由子宫内膜异位症引起的双侧卵巢皮肤转移极为罕见。在此,我们报告一名51岁女性,患有FIGO 1A期1级子宫内膜样腺癌和同步双侧1B期卵巢子宫内膜样腺癌,在全腹子宫切除术和双侧输卵管卵巢切除术后34个月出现皮肤转移。患者接受切除活检后,我们进行了姑息性放疗。放疗结束后,患者接受顺铂和阿霉素联合治疗,但疾病进展迅速,患者在入院4个月后因广泛播散性疾病死亡。

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