Gomez R S, Ozen I Y, Peters K P, Simon M, Hornstein O P
Dermatologische Klinik und Poliklinik, Universität Erlangen-Nürnberg.
Hautarzt. 1989 Jul;40(7):451-5.
A case is reported of Crohn's disease in a 17-year-old patient. The initial manifestation was bipolar: the clinical features of macrocheilitis with swelling of the upper lip that had persisted for the last 6 months. The buccal tissue disclosed a cobblestone-appearance, combined with atypical fissures and rhagades in the anogenital region. Histopathological examination of lip and anogenital biopsy specimens revealed a granulomatous inflammatory reaction. Therefore, the clinical findings were interpreted as the primary manifestation of Crohn's disease. In the differential diagnosis Melkersson-Rosenthal's syndrome was also taken into consideration.
报告了一例17岁克罗恩病患者的病例。最初表现为双相性：上唇肿大的巨唇炎临床特征持续了6个月。颊部组织呈现鹅卵石样外观，同时伴有肛门生殖器区域的非典型裂隙和皲裂。唇部和肛门生殖器活检标本的组织病理学检查显示为肉芽肿性炎症反应。因此，这些临床发现被解释为克罗恩病的主要表现。在鉴别诊断中也考虑了梅尔克森 - 罗森塔尔综合征。
