2009年至2014年巴西圣卡塔琳娜州甲型H1N1流感（pdm09）实验室确诊死亡病例
Laboratory-confirmed deaths caused by influenza A (H1N1)pdm09 in the Santa Catarina State, Brazil, 2009-2014.
作者信息
Pereira Renata da Silva Cardoso, Kupek Emil
机构信息
Programa de Pós-Graduação em Ciências Médicas, Universidade Federal de Santa Catarina, Florianópolis, Santa Catarina, Brazil.
出版信息
Rev Soc Bras Med Trop. 2016 Jul-Aug;49(4):486-90. doi: 10.1590/0037-8682-0045-2016.
INTRODUCTION
Little information is available on the evolution of influenza A (H1N1)pdm09-related mortality in Brazil.
METHODS
During the period 2009-2014, official epidemiological surveillance and mortality data were used to ascertain influenza-related deaths in the Santa Catarina State in Brazil.
RESULTS
The highest overall mortality rate (2.3 per 100,000) was observed in 2009. Pregnant women constituted the highest risk group (mortality rate 18.0 per 100,000). Following vaccination of high-risk groups, the rate reduced sharply but peaked again in 2012. It subsequently decreased, albeit more gradually.
CONCLUSIONS
Influenza A (H1N1)pdm09 mortality demonstrated a cyclic pattern, with two peaks followed by a gradual decrease.
引言
关于巴西甲型H1N1流感大流行相关死亡率的演变，目前可获取的信息较少。
方法
在2009年至2014年期间，利用官方流行病学监测和死亡率数据来确定巴西圣卡塔琳娜州与流感相关的死亡情况。
结果
2009年观察到总体死亡率最高（每10万人中有2.3人死亡）。孕妇构成了风险最高的群体（死亡率为每10万人中有18.0人死亡）。高危人群接种疫苗后，死亡率急剧下降，但在2012年再次达到峰值。随后虽有下降，但下降过程较为缓慢。
结论
甲型H1N1流感大流行的死亡率呈现出周期性模式，出现了两个峰值，随后逐渐下降。
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