Kawahara K, Kumagai S, Nakazono Y, Miyamoto Y
Department of Information Engineering, Yamagata University, Yonezawa, Japan.
J Appl Physiol (1985). 1989 Jul;67(1):110-5. doi: 10.1152/jappl.1989.67.1.110.
To determine whether and how the strength of coupling between respiratory and stepping rhythms varies depending on locomotor patterns, correlation analysis was done of diaphragmatic and gastrocnemius muscle activities. In spontaneously breathing cats decerebrated at the precollicular-post-mammillary level, tonic electrical stimulation was delivered to the mesencephalic locomotor region to induce locomotion on a treadmill. Electromyograms were recorded from the left hemidiaphragm and the bilateral gastrocnemius muscles. Various locomotor patterns were elicited by changes in the belt speed of the treadmill and in the intensity of stimulation of the mesencephalic locomotor region. Cross-correlograms between diaphragmatic and gastrocnemius activities showed that coupling was absent or weak when the cats walked slowly. The strength of locomotor-respiratory coupling tended to increase as the mean stepping interval shortened. When the animals were galloping, the respiratory rhythm was entrained 1:1 with the stepping rhythm. This study showed that the strength of coupling between respiratory and stepping rhythms varied depending on the locomotor patterns elicited, especially on whether the animals were running.
为了确定呼吸节律与踏步节律之间的耦合强度是否以及如何随运动模式而变化，对膈肌和腓肠肌的活动进行了相关性分析。在中脑前丘 - 乳头体水平去大脑的自主呼吸猫中，对中脑运动区进行强直电刺激以在跑步机上诱导运动。从左半膈肌和双侧腓肠肌记录肌电图。通过改变跑步机的皮带速度和中脑运动区的刺激强度引发各种运动模式。膈肌和腓肠肌活动之间的互相关图显示，当猫缓慢行走时，耦合不存在或较弱。随着平均踏步间隔缩短，运动 - 呼吸耦合强度趋于增加。当动物飞奔时，呼吸节律与踏步节律以1:1的比例同步。这项研究表明，呼吸节律与踏步节律之间的耦合强度随所引发的运动模式而变化，特别是取决于动物是否在奔跑。
