Fernandez-Flores Angel, Cassarino David S
Department of Cellular Pathology, Hospital El Bierzo, Ponferrada, Spain.
Department of Pathology, Southern California Kaiser Permanente, Los Angeles Medical Center (LAMC), Kaiser Permanente, Los Angeles, CA 90027-5969.
Ann Diagn Pathol. 2017 Feb;26:64-69. doi: 10.1016/j.anndiagpath.2016.08.005. Epub 2016 Aug 20.
Acral lentiginous melanoma is a rare variant of melanoma that is associated with a relatively low survival rate. The latter is partly due to the advanced stage in which the tumor is usually diagnosed. The diagnostic delay is mainly due to difficulties in identifying the very early histopathological signs of acral melanoma. The current article is a review of diagnostic clues, concepts, and definitions from the literature, as well as illustrating examples from our own archives. We have sought to provide an article that can be easily consulted in difficult cases of acral lentiginous melanoma.
肢端雀斑样痣黑色素瘤是黑色素瘤的一种罕见变体，其生存率相对较低。后者部分归因于肿瘤通常在晚期才被诊断出来。诊断延迟主要是由于难以识别肢端黑色素瘤非常早期的组织病理学特征。本文是对文献中诊断线索、概念和定义的综述，并展示了我们自己档案中的实例。我们试图提供一篇在肢端雀斑样痣黑色素瘤疑难病例中易于查阅的文章。
