Akira K, Baba S
Tokyo College of Pharmacy, Japan.
J Chromatogr. 1989 May 5;490(1):21-31. doi: 10.1016/s0378-4347(00)82757-7.
A gas chromatographic system with wide-bore capillary columns and synchronized accumulating radioisotope detector (SARD) was developed. A direct injection method and constant-flow regulation were applied. The performance of wide-bore capillary columns was good and the correspondence of the resolution obtained with SARD and that with mass detection was excellent. It was proved that the apparatus could detect of the order of 1 pg of 3H-labelled substances (3.7 TBq/mmol) and compete in terms of sensitivity with gas chromatography-mass spectrometry.
开发了一种配备宽口径毛细管柱和同步累积放射性同位素检测器（SARD）的气相色谱系统。采用了直接进样法和恒流调节。宽口径毛细管柱性能良好，SARD获得的分辨率与质谱检测的分辨率对应性极佳。事实证明，该仪器能够检测约1 pg的3H标记物质（3.7 TBq/mmol），并且在灵敏度方面可与气相色谱 - 质谱联用仪相媲美。
