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毛囊单位提取移植修复三例难治性局限性白癜风色素沉着,包括既往非培养黑素细胞-角质形成细胞移植治疗无效者

Restoration of Pigmentation by Follicular Unit Extraction Transplant in Three Cases of Focal Vitiligo Recalcitrant to Therapy including with Previous Nonculture Melanocyte-keratinocyte Transplant.

作者信息

Menon Shruti Mohankumar, Sharma Yugal K, Bansal Prakhar, Ghadgepatil Shruti S

机构信息

Department of Dermatology, Dr. D. Y. Patil Medical College and Hospital, Pimpri, Pune, Maharashtra, India.

出版信息

Int J Trichology. 2016 Apr-Jun;8(2):87-8. doi: 10.4103/0974-7753.188041.

DOI:10.4103/0974-7753.188041
PMID:27601864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4989395/
Abstract

Vitiligo is an acquired, idiopathic depigmentary disease resisting satisfactory repigmentation despite multimodal therapy. Based on the concept of activation of the existing undifferentiated stem cells in the outer root sheet of the hair follicles, follicular unit extraction (FUE) transplant is an interesting advancement in the field of minimally invasive surgery for vitiligo. We herein present three cases of vitiligo whose residual recalcitrant foci as well as poliosis - refractory to therapy including with previous nonculture melanocyte-keratinocyte transplant - repigmented satisfactorily after FUE transplant.

摘要

白癜风是一种获得性、特发性色素脱失性疾病,尽管采用了多模式治疗,但仍难以实现令人满意的色素再生。基于激活毛囊外根鞘中现存未分化干细胞的概念,毛囊单位提取(FUE)移植是白癜风微创手术领域一项有趣的进展。我们在此报告三例白癜风病例,其残留的顽固病灶以及对包括先前非培养黑素细胞-角质形成细胞移植在内的治疗均无效的白发,在FUE移植后色素再生情况令人满意。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c57/4989395/b1f0ab16d9da/IJT-8-87-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c57/4989395/b1f0ab16d9da/IJT-8-87-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c57/4989395/b1f0ab16d9da/IJT-8-87-g002.jpg

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Restoration of Pigmentation by Follicular Unit Extraction Transplant in Three Cases of Focal Vitiligo Recalcitrant to Therapy including with Previous Nonculture Melanocyte-keratinocyte Transplant.毛囊单位提取移植修复三例难治性局限性白癜风色素沉着,包括既往非培养黑素细胞-角质形成细胞移植治疗无效者
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引用本文的文献

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J Cutan Aesthet Surg. 2019 Jul-Sep;12(3):179-182. doi: 10.4103/JCAS.JCAS_61_19.
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New insights in vitiligo treatments using bioactive compounds from .

本文引用的文献

1
Follicular unit extraction hair transplant harvest: a review of current recommendations and future considerations.毛囊单位提取毛发移植采集:当前建议与未来考量综述
Dermatol Online J. 2014 Mar 17;20(3):doj_21754.
2
Standard guidelines of care for vitiligo surgery.白癜风手术的标准护理指南。
Indian J Dermatol Venereol Leprol. 2008 Jan;74 Suppl:S37-45.
3
Psychiatric morbidity in psoriasis and vitiligo: a comparative study.银屑病和白癜风患者的精神疾病发病率:一项对比研究。
利用来自……的生物活性化合物治疗白癜风的新见解
Exp Ther Med. 2019 Feb;17(2):1039-1044. doi: 10.3892/etm.2018.6977. Epub 2018 Nov 16.
J Dermatol. 2001 Aug;28(8):419-23. doi: 10.1111/j.1346-8138.2001.tb00003.x.
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Single hair grafting for the treatment of vitiligo.
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5
PUVA-induced repigmentation of vitiligo: scanning electron microscopy of hair follicles.补骨脂素加紫外线A诱导的白癜风复色:毛囊的扫描电子显微镜检查
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