在即刻乳房植入重建中对即用型Alloderm和DermACELL的直接比较。
A Direct Comparison of Alloderm-Ready to Use (RTU) and DermACELL in Immediate Breast Implant Reconstruction.
作者信息
Zenn Michael R, Salzberg C Andrew
机构信息
Duke University Medical Center, Durham, NC.
Icahn School of Medicine, Mount Sinai Health System, New York.
出版信息
Eplasty. 2016 Aug 11;16:e23. eCollection 2016.
Abstract
The objective of this study was to compare the 2 leading human acellular dermal matrices in breast reconstruction with implants. This retrospective study draws on the experience of 2 expert surgeons with a history of long-standing use of the Alloderm-RTU (LifeCell Corporation, Branchburg, NJ) product who switched to the DermACELL acellular dermal matrix (LifeNet Health, Virgina Beach, Va) product. The consecutive nature of these data over this change allowed comparison between the 2 products without the confounding effects of patient selection or change in technique. The postoperative complications of seroma, infection, implant loss, and unplanned return to the operating room were studied, and no statistical differences were noted between these 2 products. The overall complications rates were low, with implant loss and infection less than 2% in 249 cases. Recommendations are for continued use of acellular dermal matrix in breast reconstruction and product selection based on price and availability.
摘要
本研究的目的是比较两种主要的用于植入物乳房重建的人脱细胞真皮基质。这项回顾性研究借鉴了两位经验丰富的外科医生的经验，他们长期使用Alloderm-RTU（LifeCell公司，新泽西州布兰奇堡）产品，后来改用DermACELL脱细胞真皮基质（LifeNet Health公司，弗吉尼亚州弗吉尼亚海滩）产品。在这一转变过程中这些数据的连续性使得能够在不考虑患者选择或技术改变的混杂影响的情况下对两种产品进行比较。研究了血清肿、感染、植入物丢失以及计划外返回手术室等术后并发症，这两种产品之间未发现统计学差异。总体并发症发生率较低，在249例病例中，植入物丢失和感染发生率均低于2%。建议在乳房重建中继续使用脱细胞真皮基质，并根据价格和可获得性进行产品选择。
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