Shinojima Ari, Kawamura Akiyuki, Mori Ryusaburo, Fujita Kyoko, Yuzawa Mitsuko
Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, Tokyo, Japan.
Ophthalmologica. 2016;236(2):108-13. doi: 10.1159/000448436. Epub 2016 Sep 9.
To reveal vascular signals at the choriocapillaris level in central serous chorioretinopathy (CSC) using optical coherence tomographic angiography (OCTA).
We analyzed vascular signals at the choriocapillaris level in 58 CSC and 51 contralateral eyes by OCTA (RTVue XR Avanti with AngioVue; Optovue Inc., Fremont, Calif., USA). Data analysis included age, best corrected visual acuity (BCVA), disease duration and serous retinal detachment (SRD) height.
Morphologically, abnormal signals at the choriocapillaris level were detected in all CSC eyes (100%), and then classified into three patterns. Age, BCVA, disease duration and SRD height showed no significant correlation with signal patterns. Thirty-one contralateral eyes (61%) showed abnormal signals at the choriocapillaris level on OCTA, while 20 (39%) had a normal pattern.
OCTA revealed three types of abnormal signals not only in CSC eyes but also in fellow eyes without SRD. OCTA may provide information for elucidating the underlying pathogenesis of CSC.
使用光学相干断层扫描血管造影(OCTA)揭示中心性浆液性脉络膜视网膜病变(CSC)中脉络膜毛细血管层的血管信号。
我们通过OCTA(配备AngioVue的RTVue XR Avanti;美国加利福尼亚州弗里蒙特市的Optovue公司)分析了58例CSC患者的患眼及51例对侧眼脉络膜毛细血管层的血管信号。数据分析包括年龄、最佳矫正视力(BCVA)、病程和浆液性视网膜脱离(SRD)高度。
形态学上,所有CSC患眼(100%)均检测到脉络膜毛细血管层的异常信号,然后分为三种模式。年龄、BCVA、病程和SRD高度与信号模式无显著相关性。31例对侧眼(61%)在OCTA上显示脉络膜毛细血管层有异常信号,而20例(39%)模式正常。
OCTA不仅在CSC患眼中,而且在没有SRD的对侧眼中都揭示了三种类型的异常信号。OCTA可能为阐明CSC的潜在发病机制提供信息。