Woolfolk C L, Harper L M, Flick L, Mathews K, Chang J J
Department of Epidemiology, Saint Louis University College for Public Health and Social Justice, St. Louis, MO, USA.
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology. University of Alabama at Birmingham, Birmingham, AL, USA.
J Perinatol. 2016 Dec;36(12):1055-1060. doi: 10.1038/jp.2016.149. Epub 2016 Sep 8.
To examine racial differences in the association between gestational weight gain and preterm birth subtypes among adolescents.
We conducted a retrospective cohort study of 211 403 adolescents using 2012 United States natality data. The outcome was preterm birth and the primary exposure was gestational weight gain. Multinomial logistic regression analyses were used to estimate adjusted odds ratios, stratified by race and body mass index (BMI).
Black and White mothers who gained below the recommendations had increased risks for spontaneous preterm birth in all BMI categories, except obese. All Hispanic mothers who gained below the recommendations had increased risks of spontaneous preterm birth. White normal and overweight mothers and Black, Hispanic and Other normal weight mothers who exceeded the recommendations had decreased risks of spontaneous preterm birth.
The effect of gestational weight gain on spontaneous and medically indicated preterm birth is modified by race and BMI.
研究青少年妊娠期体重增加与早产亚型之间的种族差异。
我们利用2012年美国出生数据对211403名青少年进行了一项回顾性队列研究。结局为早产，主要暴露因素为妊娠期体重增加。采用多项逻辑回归分析按种族和体重指数（BMI）分层估计调整后的比值比。
体重增加未达推荐标准的黑人母亲和白人母亲，除肥胖类别外，在所有BMI类别中自发早产风险均增加。体重增加未达推荐标准的所有西班牙裔母亲自发早产风险均增加。体重增加超过推荐标准的白人正常体重和超重母亲以及黑人、西班牙裔和其他正常体重母亲自发早产风险降低。
妊娠期体重增加对自发早产和医学指征性早产的影响因种族和BMI而异。
