Asif Kaiz S, Sattar Ahsan, Lazzaro Marc A, Fitzsimmons Brian-Fred, Lynch John R, Zaidat Osama O
Departments of Neurology, Medical College of Wisconsin and Froedtert Hospital, Milwaukee, Wis., USA.
Departments of Neurology, Medical College of Wisconsin and Froedtert Hospital, Milwaukee, Wis., USA; Departments of Neurosurgery, Medical College of Wisconsin and Froedtert Hospital, Milwaukee, Wis., USA.
Interv Neurol. 2016 Jun;5(1-2):57-64. doi: 10.1159/000444662. Epub 2016 Mar 22.
Small aneurysms located at the anterior communicating artery carry significant procedural challenges due to a complex anatomy. Recent advances in endovascular technologies have expanded the use of coil embolization for small aneurysm treatment. However, limited reports describe their safety and efficacy profiles in very small anterior communicating artery aneurysms.
We sought to review and report the immediate and long-term clinical as well as radiographic outcomes of consecutive patients with ruptured very small anterior communicating artery aneurysms treated with current endovascular coil embolization techniques.
A prospectively maintained single-institution neuroendovascular database was accessed to identify consecutive cases of very small (<3 mm) ruptured anterior communicating artery aneurysms treated endovascularly between 2006 and 2013.
A total of 20 patients with ruptured very small (<3 mm) anterior communicating artery aneurysms were consecutively treated with coil embolization. The average maximum diameter was 2.66 ± 0.41 mm. Complete aneurysm occlusion was achieved for 17 (85%) aneurysms and near-complete aneurysm occlusion for 3 (15%) aneurysms. Intraoperative perforation was seen in 2 (10%) patients without any clinical worsening or need for an external ventricular drain. A thromboembolic event occurred in 1 (5 %) patient without clinical worsening or radiologic infarct. Median clinical follow-up was 12 (±14.1) months and median imaging follow-up was 12 (±18.4) months.
This report describes the largest series of consecutive endovascular treatments of ruptured very small anterior communicating artery aneurysms. These findings suggest that coil embolization of very small aneurysms in this location can be performed with acceptable rates of complications and recanalization.
由于解剖结构复杂,位于前交通动脉的小动脉瘤在手术过程中面临重大挑战。血管内技术的最新进展扩大了线圈栓塞术在小动脉瘤治疗中的应用。然而,关于其在非常小的前交通动脉动脉瘤中的安全性和有效性的报道有限。
我们旨在回顾并报告采用当前血管内线圈栓塞技术治疗的连续性破裂前交通动脉微小动脉瘤患者的近期和长期临床及影像学结果。
访问一个前瞻性维护的单机构神经血管内数据库,以确定2006年至2013年间采用血管内治疗的连续性非常小(<3mm)破裂前交通动脉动脉瘤病例。
共有20例连续性破裂前交通动脉微小(<3mm)动脉瘤患者接受了线圈栓塞治疗。平均最大直径为2.66±0.41mm。17例(85%)动脉瘤实现了完全闭塞,3例(15%)动脉瘤实现了近完全闭塞。2例(10%)患者术中出现穿孔,但无任何临床恶化情况,也无需进行脑室外引流。1例(5%)患者发生血栓栓塞事件,但无临床恶化或影像学梗死。临床随访中位数为12(±14.1)个月,影像学随访中位数为12(±18.4)个月。
本报告描述了最大系列的连续性血管内治疗破裂前交通动脉微小动脉瘤的病例。这些发现表明,在此部位对微小动脉瘤进行线圈栓塞术,并发症发生率和再通率可接受。