iPS 细胞 10 年之后

iPS Cells 10 Years Later.

出版信息

Cell. 2016 Sep 8;166(6):1356-1359. doi: 10.1016/j.cell.2016.08.043.

DOI:10.1016/j.cell.2016.08.043

Abstract

In 2006, Takahashi and Yamanaka reported the breakthrough discovery of induction of pluripotent stem cells from fibroblasts by a combination of defined factors. Ten years later, Cell editor João Monteiro brings together Shinya Yamanaka and Hans Schöler, one the original reviewers of the landmark study, to revisit the history behind the paper and its long-lasting legacy.

摘要

2006 年，高桥和山中伸弥报道了通过组合特定因子从成纤维细胞中诱导多能干细胞的突破性发现。十年后，细胞编辑 João Monteiro 将山中伸弥和 Hans Schöler 召集在一起，后者是该里程碑研究的原始审稿人之一，共同回顾该论文背后的历史及其持久的影响。