Chen Annie S, Drummond Katharine J, Jallad Mohamad M, Paldor Iddo
Department of Neurosurgery, Royal Melbourne Hospital, 300 Grattan St, Parkville, VIC 3050, Australia.
Department of Neurosurgery, Royal Melbourne Hospital, 300 Grattan St, Parkville, VIC 3050, Australia; Department of Surgery, University of Melbourne, Melbourne, VIC, Australia.
J Clin Neurosci. 2016 Nov;33:225-227. doi: 10.1016/j.jocn.2016.03.030. Epub 2016 Sep 6.
Meningiomas are a common central nervous system tumour and radiation is a known risk factor for their development. In utero radiation exposure correlates to developmental abnormalities and carcinogenesis in a dose- and gestational age-related manner. Radiation induced meningioma has been reported in detail in the literature in patients who had been irradiated earlier in life. At the time of publication, there was no data on radiation exposure whilst in utero and meningioma. We report on a 42-year-old woman with multiple intracranial meningiomas and no other risk factors except a history of in utero exposure to low dose X-ray radiation at 12weeks gestational age.
脑膜瘤是一种常见的中枢神经系统肿瘤，而辐射是其已知的发病风险因素。子宫内辐射暴露与发育异常和致癌作用呈剂量和胎龄相关。文献中已详细报道了早年接受过辐射的患者发生辐射诱发的脑膜瘤。在发表本文时，尚无关于子宫内辐射暴露与脑膜瘤关系的数据。我们报告了一名42岁女性，患有多发性颅内脑膜瘤，除了在孕12周时子宫内暴露于低剂量X射线辐射外，无其他风险因素。
