Savaris M, Santos V Dos, Brandalise R N
University of Caxias do Sul (UCS) - Center for Exact Sciences and Technology (CCET), Francisco Getúlio Vargas Street, 1130, Caxias do Sul, 95070-560, RS, Brazil.
University of Caxias do Sul (UCS) - Center for Exact Sciences and Technology (CCET), Francisco Getúlio Vargas Street, 1130, Caxias do Sul, 95070-560, RS, Brazil.
Mater Sci Eng C Mater Biol Appl. 2016 Dec 1;69:661-7. doi: 10.1016/j.msec.2016.07.031. Epub 2016 Jul 15.
This study aims at analyzing the modifications in the morphological, physical, chemical and thermal properties of commercial poly(lactic acid) (PLA) films after exposure to five different sterilization processes. Films were obtained by compression molding, hygienized and sterilized by ethylene oxide (SEtO), hydrogen peroxide plasma (SH2O2), saturated steam (SSS), electron beam radiation (SEB) and gamma radiation (SGR). The samples of PLASEtO, PLASH2O2, PLASEB and PLASGR exhibited thermal and physical changes after being submitted to sterilization processes. PLASSS showed morphological, chemical, thermal and physical changes. It is concluded that processes by SEtO, SH2O2, SEB and EGR can be applied for the sterilization of PLA films and the SSS process is not recommended in view of the data obtained and test conditions reported in this study for PLA films.
本研究旨在分析市售聚乳酸（PLA）薄膜在经过五种不同灭菌工艺处理后，其形态、物理、化学和热性能的变化。薄膜通过压缩成型制得，分别采用环氧乙烷（SEtO）、过氧化氢等离子体（SH2O2）、饱和蒸汽（SSS）、电子束辐射（SEB）和伽马辐射（SGR）进行卫生处理和灭菌。PLASEtO、PLASH2O2、PLASEB和PLASGR的样品在经过灭菌处理后呈现出热性能和物理性能的变化。PLASSS则表现出形态、化学、热性能和物理性能的变化。结论是，根据本研究针对PLA薄膜所获得的数据和测试条件，SEtO、SH2O2、SEB和EGR工艺可用于PLA薄膜的灭菌，而SSS工艺不推荐使用。
