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非裔美国吸烟者中基于群体的特定文化认知行为疗法的随机对照试验

Randomized Controlled Trial of Group-Based Culturally Specific Cognitive Behavioral Therapy Among African American Smokers.

作者信息

Webb Hooper Monica, Antoni Michael H, Okuyemi Kolawole, Dietz Noella A, Resnicow Ken

机构信息

Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH.

Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, MN.

出版信息

Nicotine Tob Res. 2017 Mar 1;19(3):333-341. doi: 10.1093/ntr/ntw181.

Abstract

INTRODUCTION

This study tested the efficacy of group-based culturally specific cognitive behavioral therapy (CBT) for smoking cessation among low-income African Americans.

METHODS

Participants (N = 342; 63.8% male; M = 49.5 years old; M cigarettes per day = 18) were randomly assigned to eight sessions of group-based culturally specific or standard CBT, plus 8 weeks of transdermal nicotine patches. Biochemically verified 7-day point prevalence abstinence (ppa) was assessed at the end-of-therapy (ie, CBT) (EOT), and 3-, 6-, and 12-month follow-ups. Primary outcomes were the longitudinal intervention effect over the 12-month follow-up period, and 7-day ppa at the 6-month follow-up. Secondary outcomes included 7-day ppa at the EOT and 12-month follow-up, and intervention ratings. Generalized linear mixed modeling tested the longitudinal effect and logistic regression tested effects at specific timepoints.

RESULTS

Generalized linear mixed modeling demonstrated a longitudinal effect of intervention condition. Specifically, 7-day ppa was two times (P = .02) greater following culturally specific CBT versus standard CBT when tested across all timepoints. Analyses by timepoint found no significant difference at 6 or 12 months, yet culturally specific CBT was efficacious at the EOT (62.5% vs. 51.5% abstinence, P = .05) and the 3-month follow-up (36.4% vs. 22.9% abstinence, P = .007). Finally, intervention ratings in both conditions were high, with no significant differences.

CONCLUSIONS

Culturally specific CBT had a positive longitudinal effect on smoking cessation compared to a standard approach; however, the effects were driven by short-term successes. We recommend the use of group-based culturally specific CBT in this population when possible, and future research on methods to prevent long-term relapse.

IMPLICATIONS

Culturally specific interventions are one approach to address smoking-related health disparities; however, evidence for their efficacy in African Americans is equivocal. Moreover, the methodological limitations of the existing literature preclude an answer to this fundamental question. We found a positive longitudinal effect of culturally specific CBT versus standard CBT for smoking cessation across the follow-up period. Analyses by assessment point revealed that the overall effect was driven by early successes. Best practices for treating tobacco use in this population should attend to ethnocultural factors, but when this is not possible, standard CBT is an alternative approach for facilitating long-term abstinence.

摘要

引言

本研究测试了基于群体的具有文化特异性的认知行为疗法(CBT)对低收入非裔美国人戒烟的疗效。

方法

参与者(N = 342;63.8%为男性;平均年龄M = 49.5岁;每日吸烟量M = 18支)被随机分配到八节基于群体的具有文化特异性的CBT课程或标准CBT课程中,并接受8周的经皮尼古丁贴片治疗。在治疗结束时(即CBT结束时)(EOT)以及3个月、6个月和12个月的随访时,评估经生化验证的7天点患病率戒断率(ppa)。主要结局是12个月随访期内的纵向干预效果,以及6个月随访时的7天ppa。次要结局包括EOT和12个月随访时的7天ppa,以及干预评分。广义线性混合模型测试纵向效果,逻辑回归测试特定时间点的效果。

结果

广义线性混合模型显示了干预条件的纵向效果。具体而言,在所有时间点进行测试时,与标准CBT相比,具有文化特异性的CBT后的7天ppa高出两倍(P = 0.02)。按时间点分析发现在6个月或12个月时无显著差异,但具有文化特异性的CBT在EOT时有效(戒断率分别为62.5%和51.5%,P = 0.05),在3个月随访时也有效(戒断率分别为36.4%和22.9%,P = 0.007)。最后,两种条件下的干预评分都很高,且无显著差异。

结论

与标准方法相比,具有文化特异性的CBT对戒烟有积极的纵向效果;然而,这些效果是由短期成功驱动的。我们建议尽可能在该人群中使用基于群体的具有文化特异性的CBT,并对预防长期复吸的方法进行未来研究。

启示

具有文化特异性的干预措施是解决与吸烟相关的健康差距的一种方法;然而,其在非裔美国人中的疗效证据并不明确。此外,现有文献的方法学局限性无法回答这个基本问题。我们发现,在整个随访期内,具有文化特异性的CBT与标准CBT相比,对戒烟有积极的纵向效果。按评估点分析表明,总体效果是由早期成功驱动的。在该人群中治疗烟草使用的最佳实践应关注种族文化因素,但如果无法做到这一点,标准CBT是促进长期戒烟的另一种方法。

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