Grupo de Enfermedades Infecciosas, Clínica De La Mujer, Bogotá, Colombia.
Programa de Pós-Graduação em Doenças Infecciosas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Vitória, Brazil.
J Infect Public Health. 2017 May-Jun;10(3):353-356. doi: 10.1016/j.jiph.2016.08.012. Epub 2016 Sep 7.
Spoted fever group (SFG) rickettsioses are actually considered as emerging and re-emerging zoonotic diseases, caused by pathogenic bacteria of the spotted fever group rickettsiae (SFGR). Recently, serologic studies in human and animals conducted in Colombian Orinoquia, showed a high seroprevalence against SFGR. In June 2015, a 50-year-old male was admitted to a hospital in Bogotá, Colombia, with two days of malaise and temperature of 39°C, associated to generalized rash 24h after the onset of fever. He referred a work visit and outdoor activities in rural area of the Department of Meta 15days prior the onset of symptoms. The patient was transferred to the intensive care unit with supplementary oxygen, inotropic support and was assessed by the infectious diseases department, indicating the addition of Doxycycline. After seven days of antibiotic treatment the patient was discharged with no evidence of new symptoms or sequels. Retrospectively, two serum samples collected during the acute and convalescent phase were evaluated; there was four fold rise in titer against SFGR. With the foregoing, associated with the recent serological evidence that suggests the circulation of SFGR species in the Colombian Orinoquia, we consider to recognize this region as a new endemic area for SFG Rickettsioses.
斑点热群(SFG)立克次体病实际上被认为是新发和再发的人畜共患病,由斑点热群立克次体(SFGR)引起的致病性细菌引起。最近,在哥伦比亚奥里诺科进行的人类和动物血清学研究显示,针对 SFGR 的血清阳性率很高。2015 年 6 月,一名 50 岁男性因不适和体温 39°C 入住哥伦比亚波哥大的一家医院,发烧后 24 小时出现全身性皮疹。他报告了在症状发作前 15 天在 Meta 部门农村地区的一次工作访问和户外活动。该患者被转至重症监护病房,给予补充氧气、正性肌力支持,并由传染病科评估,表明添加了强力霉素。在抗生素治疗七天后,患者出院,没有新症状或后遗症的证据。回顾性地,评估了在急性期和恢复期采集的两份血清样本;针对 SFGR 的滴度升高了四倍。有鉴于此,再加上最近的血清学证据表明 SFGR 种在哥伦比亚奥里诺科的循环,我们认为将该地区确认为 SFG 立克次体病的新流行区。