Tan Tze King, Tan Ka Yun, Hari Ranjeev, Mohamed Yusoff Aini, Wong Guat Jah, Siow Cheuk Chuen, Mutha Naresh V R, Rayko Mike, Komissarov Aleksey, Dobrynin Pavel, Krasheninnikova Ksenia, Tamazian Gaik, Paterson Ian C, Warren Wesley C, Johnson Warren E, O'Brien Stephen J, Choo Siew Woh
Genome Informatics Research Laboratory, Centre for Research in Biotechnology for Agriculture (CEBAR), High Impact Research Building, University of Malaya, 50603 Kuala Lumpur, Malaysia Department of Oral and Craniofacial Sciences, Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Genome Informatics Research Laboratory, Centre for Research in Biotechnology for Agriculture (CEBAR), High Impact Research Building, University of Malaya, 50603 Kuala Lumpur, Malaysia Institute of Biology Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur Malaysia.
Database (Oxford). 2016 Sep 11;2016. doi: 10.1093/database/baw063. Print 2016.
Pangolins (order Pholidota) are the only mammals covered by scales. We have recently sequenced and analyzed the genomes of two critically endangered Asian pangolin species, namely the Malayan pangolin (Manis javanica) and the Chinese pangolin (Manis pentadactyla). These complete genome sequences will serve as reference sequences for future research to address issues of species conservation and to advance knowledge in mammalian biology and evolution. To further facilitate the global research effort in pangolin biology, we developed the Pangolin Genome Database (PGD), as a future hub for hosting pangolin genomic and transcriptomic data and annotations, and with useful analysis tools for the research community. Currently, the PGD provides the reference pangolin genome and transcriptome data, gene sequences and functional information, expressed transcripts, pseudogenes, genomic variations, organ-specific expression data and other useful annotations. We anticipate that the PGD will be an invaluable platform for researchers who are interested in pangolin and mammalian research. We will continue updating this hub by including more data, annotation and analysis tools particularly from our research consortium.Database URL: http://pangolin-genome.um.edu.my.
穿山甲（鳞甲目）是唯一身披鳞片的哺乳动物。我们最近对两种极度濒危的亚洲穿山甲物种，即马来穿山甲（马来穿山甲属）和中华穿山甲（中华穿山甲属）的基因组进行了测序和分析。这些完整的基因组序列将作为未来研究的参考序列，以解决物种保护问题，并推动哺乳动物生物学和进化领域的知识发展。为了进一步促进全球穿山甲生物学研究工作，我们开发了穿山甲基因组数据库（PGD），作为未来托管穿山甲基因组和转录组数据及注释的中心，并为研究界提供有用的分析工具。目前，PGD提供了参考穿山甲基因组和转录组数据、基因序列和功能信息、表达的转录本、假基因、基因组变异、器官特异性表达数据及其他有用的注释。我们预计PGD将成为对穿山甲和哺乳动物研究感兴趣的研究人员的宝贵平台。我们将继续更新这个中心，特别是纳入更多来自我们研究联盟的数据、注释和分析工具。数据库网址：http://pangolin-genome.um.edu.my
