Khan Lubna, Malukani Kamal, Malaiya Siddharth, Yeshwante Prashant, Ishrat Saba, Nandedkar Shirish S
Department of Ophthalmology, Sri Aurobindo Institute of Medical Sciences, Indore, Madhya Pradesh, India.
Department of Pathology, Sri Aurobindo Institute of Medical Sciences, Indore, Madhya Pradesh, India.
J Ophthalmic Vis Res. 2016 Jul-Sep;11(3):287-95. doi: 10.4103/2008-322X.188397.
To evaluate the role of fine needle aspiration (FNAC) as a diagnostic tool in cases of orbital and ocular adnexal masses. Cytological findings were correlated with histopathological diagnosis wherever possible.
FNAC was performed in 29 patients of different age groups presenting with orbital and ocular adnexal masses. Patients were evaluated clinically and investigated by non-invasive techniques before fine needle aspiration of the masses. Smears were analyzed by a cytologist in all cases. Further, results of cytology were compared with the histopathological diagnosis.
The age of patients ranged from 1 to 68 years (mean: 29.79±19.29). There were 14 males and 15 females with a male to female ratio of 0.93:1. Out of 29 cases, 26 aspirates were cellular. Cellularity was insufficient in three (10.34%) aspirates. Out of 26 cellular aspirates, 11 were non-neoplastic while 15 were neoplastic on cytology. Subsequent histopathologic examination was done in 21/26 cases. Concordance rate of FNAC in orbital and ocular adnexal mass lesions with respect to the precise histologic diagnosis was 90%.
When properly used in well-indicated patients (in cases where a diagnosis cannot be made by clinical and imaging findings alone), FNAC of orbital and periorbital lesions is an invaluable and suitable adjunct diagnostic technique that necessitates close cooperation between the ophthalmologist and cytologist. However, nondiagnostic aspirates may sometimes be obtained, and an inconclusive FNAC should not always be ignored.
评估细针穿刺抽吸活检(FNAC)在眼眶及眼附属器肿物病例中作为诊断工具的作用。尽可能将细胞学检查结果与组织病理学诊断结果进行对比。
对29例患有眼眶及眼附属器肿物的不同年龄组患者进行FNAC。在对肿物进行细针穿刺抽吸之前,先对患者进行临床评估并采用非侵入性技术进行检查。所有病例的涂片均由细胞学家进行分析。此外,将细胞学检查结果与组织病理学诊断结果进行比较。
患者年龄范围为1至68岁(平均:29.79±19.29)。男性14例,女性15例,男女比例为0.93:1。29例病例中,26例抽吸物有细胞成分。3例(10.34%)抽吸物细胞数量不足。在26例有细胞成分的抽吸物中,细胞学检查显示11例为非肿瘤性,15例为肿瘤性。随后对26例中的21例进行了组织病理学检查。FNAC在眼眶及眼附属器肿物病变中关于精确组织学诊断的符合率为90%。
当在适应证明确的患者中正确使用时(即在仅通过临床和影像学检查无法做出诊断的情况下),眼眶及眶周病变的FNAC是一种非常有价值且合适的辅助诊断技术,这需要眼科医生和细胞学家密切合作。然而,有时可能会获得无法诊断的抽吸物,且不应总是忽视不确定的FNAC结果。