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[原发性慢性肾上腺皮质功能减退症的各项免疫学指标]

[Various immunologic indices in primary chronic adrenal insufficiency].

作者信息

Sil'nitskiĭ P A, Shabanova L F, Georgadze E R, Sirotina V V

出版信息

Probl Endokrinol (Mosk). 1989 May-Jun;35(3):3-7.

PMID:2762261
Abstract

Patients with primary chronic adrenal insufficiency (PCAI) in decompensation demonstrated a decrease in the total level of blood immunoglobulins, in particular IgG, with the normal level of B-lymphocytes. A decrease in IgG and an increase in IgA content was noted in the eucorticoid state; relative and absolute lymphocytosis determined by an increase in T- and B-lymphocytes was also noted. In overdosage of cortisone acetate the total number of immunoglobulins was normal, but IgA was raised and IgG lowered. The number of B-lymphocytes was significantly elevated. The number of T-lymphocytes was within normal but an increase in the level of T-suppressors was noted.

摘要

失代偿期原发性慢性肾上腺皮质功能减退症(PCAI)患者的血液免疫球蛋白总量降低,尤其是IgG,而B淋巴细胞水平正常。在皮质激素正常状态下,IgG降低,IgA含量增加;还观察到T淋巴细胞和B淋巴细胞增多导致的相对和绝对淋巴细胞增多。醋酸可的松过量时,免疫球蛋白总数正常,但IgA升高,IgG降低。B淋巴细胞数量显著升高。T淋巴细胞数量在正常范围内,但观察到T抑制细胞水平升高。

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