Osawa Yusuke, Arai Yasumichi, Oguma Yuko, Hirata Takumi, Abe Yukiko, Azuma Koichiro, Takayama Michiyo, Hirose Nobuyoshi
J Aging Phys Act. 2017 Apr;25(2):189-195. doi: 10.1123/japa.2015-0203. Epub 2016 Sep 6.
This study investigated the relationships between muscle echo intensity (EI), physical activity (PA), and functional mobility in 108 Japanese (88-92 years). We measured EI and muscle thickness (MT) at the midpoint of the anterior superior iliac spine and patella using B-mode ultrasound. Light and moderate-to-vigorous PA (LPA and MVPA) were assessed with a triaxial accelerometer. The timed up and go (TUG) test was used to measure for functional mobility. EI, but not MT, was significantly associated with both TUG scores (β = 0.17, p = .047) and MVPA (β = -0.31, p = .01) when adjusted by potential confounders. However, association between EI and TUG disappeared after adjusted for MVPA. Meanwhile, MVPA was significantly associated with TUG scores independent of EI (β = -0.35, p < .001). Although EI of anterior thigh muscles might be a weaker predictor of functional morbidity than MVPA, it is a noninvasive and practical approach for assessing muscle quality in the very old.
本研究调查了108名88至92岁日本老年人的肌肉回声强度（EI）、身体活动（PA）与功能移动性之间的关系。我们使用B超在髂前上棘和髌骨中点测量EI和肌肉厚度（MT）。使用三轴加速度计评估轻度和中度至剧烈身体活动（LPA和MVPA）。采用定时起立行走（TUG）测试来测量功能移动性。在对潜在混杂因素进行调整后，EI而非MT与TUG评分（β = 0.17，p = 0.047）和MVPA（β = -0.31，p = 0.01）均显著相关。然而，在对MVPA进行调整后，EI与TUG之间的关联消失。同时，MVPA与TUG评分显著相关，且独立于EI（β = -0.35，p < 0.001）。尽管大腿前侧肌肉的EI可能比MVPA对功能发病的预测能力更弱，但它是评估高龄人群肌肉质量的一种非侵入性且实用的方法。
