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结构新鲜骨软骨异体移植治疗高活动量人群距骨骨软骨损伤的结果及功能预后

Results and Functional Outcomes of Structural Fresh Osteochondral Allograft Transfer for Treatment of Osteochondral Lesions of the Talus in a Highly Active Population.

作者信息

Orr Justin D, Dunn John C, Heida Kenneth A, Kusnezov Nicholas A, Waterman Brian R, Belmont Philip J

机构信息

Department of Orthopaedic Surgery, William Beaumont Army Medical Center, Texas Tech University Health Sciences Center, El Paso, Texas.

出版信息

Foot Ankle Spec. 2017 Apr;10(2):125-132. doi: 10.1177/1938640016666924. Epub 2016 Sep 20.

Abstract

INTRODUCTION

Structural fresh osteochondral allograft transfer is an appropriate treatment option for large osteochondral lesions of the talus (OLTs), specifically lesions involving the shoulder of the talus. Sparse literature exists regarding functional outcome following this surgery in high-demand populations.

MATERIALS AND METHODS

Over a 2-year period, a single surgeon performed 8 structural allograft transfers for treatment of large OLTs in an active duty US military population. Lesion morphology and magnetic resonance imaging (MRI) stage were recorded. Preoperative and latest postoperative American Orthopaedic Foot and Ankle Society (AOFAS) hindfoot-ankle and pain visual analog scores were compared.

RESULTS

Eight male service members with mean age 34.4 years underwent structural allograft transfer for OLTs with mean MRI stage of 4.9 and a mean lesion volume of 2247.1 mm. Preoperative mean AOFAS hindfoot-ankle score was 49.6, and mean pain visual analog score was 6.9. At mean follow-up of 28.5 months, postoperative mean AOFAS score was 73, and mean pain visual analog score was 4.5, representing overall improvements of 47% and 35%, respectively. Three patients were considered treatment failures secondary to continued ankle disability (2) or graft resorption requiring ankle arthrodesis.

CONCLUSIONS

Despite modest improvements in short-term functional outcome scores, large osteochondral lesions requiring structural allograft transfer remain difficult to treat, particularly in high-demand patient populations. Surgeons should counsel patients preoperatively on realistic expectations for return to function following structural allograft transfer procedures.

LEVELS OF EVIDENCE

Level IV: Retrospective study.

摘要

引言

结构性新鲜骨软骨异体移植是治疗距骨大的骨软骨损伤(OLTs),特别是累及距骨肩部损伤的一种合适治疗选择。关于这种手术在高需求人群中的功能结果的文献稀少。

材料与方法

在2年期间,一名外科医生对美国现役军人中8例大的OLTs进行了结构性异体移植治疗。记录病变形态和磁共振成像(MRI)分期。比较术前和最新术后美国矫形足踝协会(AOFAS)后足-踝关节评分和疼痛视觉模拟评分。

结果

8名平均年龄34.4岁的男性军人接受了OLTs的结构性异体移植,平均MRI分期为4.9,平均病变体积为2247.1mm。术前平均AOFAS后足-踝关节评分为49.6,平均疼痛视觉模拟评分为6.9。平均随访28.5个月时,术后平均AOFAS评分为73,平均疼痛视觉模拟评分为4.5,分别代表总体改善47%和35%。3例患者因持续的踝关节功能障碍(2例)或需要踝关节融合的移植物吸收而被视为治疗失败。

结论

尽管短期功能结果评分有适度改善,但需要结构性异体移植的大的骨软骨损伤仍然难以治疗,特别是在高需求患者人群中。外科医生应在术前向患者咨询关于结构性异体移植手术后恢复功能的现实期望。

证据水平

IV级:回顾性研究。

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