Berg Hannah E, Ballard Elizabeth D, Luckenbaugh David A, Nugent Allison C, Ionescu Dawn F, Zarate Carlos A
Experimental Therapeutics & Pathophysiology Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD.
Experimental Therapeutics & Pathophysiology Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD.
Compr Psychiatry. 2016 Oct;70:1-8. doi: 10.1016/j.comppsych.2016.06.007. Epub 2016 Jun 14.
Anxiety and depression have each been independently associated with impairments in emotional face recognition. However, little is known about the nature of these impairments when anxiety and depression co-occur.
This post-hoc analysis evaluated the relationship between anxiety status and performance on the Emotional Expression Multimorph Task within a clinical sample of individuals with major depressive disorder (MDD).
Participants with anxious depression (n=14) and nonanxious depression (n=14) completed the Emotional Expression Multimorph Task. Those with anxious depression required greater intensity of emotion to identify both happy (p=.01) and sad (p=.04) facial expressions than those with nonanxious depression. Severity of anxiety also correlated with greater intensity of emotion required to detect sad faces. Contrary to prediction, hypervigilance to angry and fearful facial expressions was not observed in anxious depression.
The present study did not include an anxiety-only group for comparison, and did not assess state anxiety at time of administration. In addition, the extent to which the experimental task correlates with social functioning is not fully understood.
These findings suggest a diminished sensitivity to happy and sad facial expressions specific to anxious depression, but not a hypervigilance toward threatening facial expressions. Further research on the nature of emotion recognition in anxiety and depression may inform improved clinical interventions.
焦虑和抑郁各自都与情绪面孔识别受损独立相关。然而,当焦虑和抑郁同时出现时,对于这些损伤的本质却知之甚少。
这项事后分析评估了在重度抑郁症(MDD)患者的临床样本中,焦虑状态与情绪表达多形态任务表现之间的关系。
伴有焦虑性抑郁的参与者(n = 14)和非焦虑性抑郁的参与者(n = 14)完成了情绪表达多形态任务。与非焦虑性抑郁的参与者相比,伴有焦虑性抑郁的参与者识别开心(p = 0.01)和悲伤(p = 0.04)面部表情需要更强的情绪强度。焦虑的严重程度也与检测悲伤面孔所需的更强情绪强度相关。与预测相反,在焦虑性抑郁中未观察到对愤怒和恐惧面部表情的过度警觉。
本研究未纳入仅患有焦虑症的组进行比较,并且在施测时未评估状态焦虑。此外,实验任务与社会功能的相关程度尚未完全了解。
这些发现表明,焦虑性抑郁对开心和悲伤面部表情的敏感性降低,但对威胁性面部表情不存在过度警觉。对焦虑和抑郁中情绪识别本质进行进一步研究可能有助于改进临床干预措施。