Schick Tina, Ersoy Lebriz, Kirchhof Bernd, Liakopoulos Sandra
Cologne Image Reading Center, Department of Ophthalmology, University Hospital of Cologne, Germany.
GMS Ophthalmol Cases. 2014 Oct 27;4:Doc06. doi: 10.3205/oc000019. eCollection 2014.
To describe asymmetrical disappearance of reticular pseudodrusen (RPD) in patients with age-related macular degeneration (AMD).
SDOCTs and infrared images of four patients with RPD were retrospectively collected and evaluated during long-term follow-up of up to 47 months (range 35-47 months).
Unilateral fading of RPD was detected on SDOCTs and infrared images in eyes with and without choroidal neovascularisation (CNV) and intravitreal injections. Presence of RPD in the fellow eyes remained stable in three cases, in one case very few RPD newly developed. Three of the four cases demonstrated unilateral outer retinal atrophy following regression of RPD.
This report highlights that RPD may almost completely disappear after occurrence and treatment of CNV in neovascular AMD, but also in dry AMD without any treatment and that this phenomenon may be unilateral.
描述年龄相关性黄斑变性（AMD）患者中网状假性玻璃膜疣（RPD）的不对称消失情况。
回顾性收集4例RPD患者的频域光学相干断层扫描（SDOCT）图像和红外图像，并在长达47个月（范围35 - 47个月）的长期随访中进行评估。
在有和没有脉络膜新生血管（CNV）以及玻璃体腔内注射的眼中，SDOCT图像和红外图像均检测到RPD的单侧消退。在3例对侧眼中，RPD的存在保持稳定，1例对侧眼中有极少数新出现的RPD。4例患者中有3例在RPD消退后出现单侧视网膜外层萎缩。
本报告强调，RPD在新生血管性AMD中CNV发生和治疗后，甚至在未经任何治疗的干性AMD中，可能几乎完全消失，且这种现象可能是单侧的。
