Zhang Mingzheng, Pu Fang, Xu Liqiang, Zhang Linlin, Liang Hang, Li Deyu, Wang Yu, Fan Yubo
a Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education , School of Biological Science and Medical Engineering, Beihang University , Beijing , P.R. China.
b State Key Laboratory of Virtual Reality Technology and Systems , Beihang University , Beijing , P.R. China.
Comput Methods Biomech Biomed Engin. 2017 Mar;20(4):355-364. doi: 10.1080/10255842.2016.1233401. Epub 2016 Sep 14.
Spinal cages are used to create a suitable mechanical environment for interbody fusion in cases of degenerative spinal instability. Due to individual variations in bone structures and pathological conditions, patient-specific cages can provide optimal biomechanical conditions for fusion, strengthening patient recovery. Finite element analysis (FEA) is a valuable tool in the biomechanical evaluation of patient-specific cage designs, but the time- and labor-intensive process of modeling limits its clinical application. In an effort to facilitate the design and analysis of patient-specific spinal cages, an integrated CAD-FEA system (CASCaDeS, comprehensive analytical spinal cage design system) was developed. This system produces a biomechanical-based patient-specific design of spinal cages and is capable of rapid implementation of finite element modeling. By comparison with commercial software, this system was validated and proven to be both accurate and efficient. CASCaDeS can be used to design patient-specific cages with a superior biomechanical performance to commercial spinal cages.
脊柱融合器用于在退行性脊柱不稳定的情况下为椎间融合创造合适的力学环境。由于骨骼结构和病理状况的个体差异，定制的融合器可为融合提供最佳的生物力学条件，促进患者康复。有限元分析（FEA）是评估定制融合器生物力学的重要工具，但建模过程耗时费力，限制了其临床应用。为了便于定制脊柱融合器的设计与分析，开发了一种集成的计算机辅助设计-有限元分析系统（CASCaDeS，综合分析脊柱融合器设计系统）。该系统基于生物力学生成定制的脊柱融合器设计，并能够快速实现有限元建模。通过与商业软件比较，该系统得到验证，证明既准确又高效。CASCaDeS可用于设计生物力学性能优于商用脊柱融合器的定制融合器。
