Jeraq Mohammed, Cote David J, Smith Timothy R
Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, 15 Francis Street - PBB3, Boston, MA, 02115, USA.
Adv Exp Med Biol. 2017;906:215-228. doi: 10.1007/5584_2016_117.
Venous thromboembolism (VTE) is a common medical condition, particularly after surgical interventions. Many studies have shown that development of VTE, including both deep vein thrombosis (DVT) and pulmonary embolism (PE), is more common in surgical patients with cancer than in patients without cancer. This chapter focuses on VTE in brain tumor patients, including their pathogenesis, presentation, diagnosis, and treatment. Topics discussed included a brief overview of VTE followed by an in-depth discussion of the VTE risks brain tumor patients face in the post-operative period. We conclude with a summary of various recommendations on VTE prophylaxis and a discussion of the controversial nature of VTE chemoprophylaxis for patients undergoing transcranial operations for brain tumors.
静脉血栓栓塞症（VTE）是一种常见的病症，尤其是在外科手术后。许多研究表明，包括深静脉血栓形成（DVT）和肺栓塞（PE）在内的VTE在患有癌症的外科手术患者中比在无癌症患者中更为常见。本章重点关注脑肿瘤患者的VTE，包括其发病机制、临床表现、诊断和治疗。讨论的主题包括VTE的简要概述，随后深入讨论脑肿瘤患者在术后面临的VTE风险。我们最后总结了关于VTE预防的各种建议，并讨论了脑肿瘤经颅手术患者VTE化学预防的争议性。
