Key Laboratory of Plant Functional Genomics, Ministry of Education, Yangzhou University, Yangzhou 225009, China.
State Key Laboratory of Rice Biology, China National RiceResearch Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310006, China.
J Integr Plant Biol. 2018 Feb;60(2):89-93. doi: 10.1111/jipb.12501. Epub 2016 Nov 1.
Grain yield is one of the most important and complex trait for genetic improvement in crops; it is known to be controlled by a number of genes known as quantitative trait loci (QTLs). In the past decade, many yield-contributing QTLs have been identified in crops. However, it remains unclear whether those QTLs confer the same yield performance in different genetic backgrounds. Here, we performed CRISPR/Cas9-mediated QTL editing in five widely-cultivated rice varieties and revealed that the same QTL can have diverse, even opposing, effects on grain yield in different genetic backgrounds.
粮食产量是作物遗传改良中最重要和最复杂的性状之一，已知它受许多被称为数量性状位点（QTLs）的基因控制。在过去的十年中，许多作物的产量贡献 QTL 已经被鉴定出来。然而，目前还不清楚这些 QTL 是否在不同的遗传背景下具有相同的产量表现。在这里，我们在五个广泛种植的水稻品种中进行了 CRISPR/Cas9 介导的 QTL 编辑，并揭示了相同的 QTL 在不同的遗传背景下对粮食产量可能具有不同的甚至相反的影响。
