Zhang Tao, Wang Zhengwei, Liu Qiaoquan, Zhao Dongsheng
Key Laboratory of Plant Functional Genomics of the Ministry of Education / Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding, Zhongshan Biological Breeding Laboratory, College of Agriculture, Yangzhou University, Yangzhou, 225009, China.
Rice (N Y). 2025 Jan 27;18(1):3. doi: 10.1186/s12284-025-00758-8.
Rice grain size influences both grain yield and quality, making it a significant target for rice genetic improvement. In recent years, numerous genes related to grain size with differential effects have been cloned. The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) gene editing system is a convenient tool for modifying genes. The use of the CRISPR/Cas9 tool for the genetic improvement of grain size-related genes is worth exploring. This paper summarizes the known grain size-related genes and the use of CRISPR/Cas9 for grain size modification and discusses the potential applications of CRISPR/Cas9 for improving rice grain size.
水稻粒型影响产量和品质，是水稻遗传改良的重要目标。近年来，已克隆出众多对粒型有不同影响的相关基因。成簇规律间隔短回文重复序列（CRISPR）/CRISPR相关蛋白9（Cas9）基因编辑系统是一种便捷的基因修饰工具。利用CRISPR/Cas9工具对粒型相关基因进行遗传改良值得探索。本文总结了已知的粒型相关基因以及CRISPR/Cas9在粒型改良中的应用，并探讨了CRISPR/Cas9在改善水稻粒型方面的潜在应用。
