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开放性骨折的当前治疗方法:在线调查结果

Current management of open fractures: results from an online survey.

作者信息

Gümbel Denis, Matthes Gerrit, Napp Matthias, Lange Jörn, Hinz Peter, Spitzmüller Romy, Ekkernkamp Axel

机构信息

Department of Trauma, Reconstructive Surgery and Rehabilitation Medicine, Ferdinand-Sauerbruch-Str., 17475, Greifswald, Germany.

Department of Trauma and Orthopaedic Surgery, BG Klinikum Unfallkrankenhaus Berlin gGmbH, Warener Str. 7, 12683, Berlin, Germany.

出版信息

Arch Orthop Trauma Surg. 2016 Dec;136(12):1663-1672. doi: 10.1007/s00402-016-2566-x. Epub 2016 Sep 15.

Abstract

BACKGROUND

Open fractures are orthopaedic emergencies that carry a high risk for infection, non-union and soft tissue complications. Evidence-based treatment is impeded by the lack of high-quality evidence-based studies. The aim of this investigation was to elucidate the current practice of open fracture management in Germany and to determine major differences in treatment.

METHODS

Surgeons were asked to complete an online questionnaire consisting of 45 items developed by an expert consensus. The first part covered questions on general principles of open fracture management. The second part included questions on soft tissue management, the preferred method of initial surgical stabilisation, microbiological testing, employment of pulsatile lavage and local antibiotics, antibiotic regimen, second-look operations, and blood testing.

RESULTS

Of 653 respondents, 364 (65 %) completed the first part and 314 (48 %) completed the second part of the online survey. 55 % answered that a standard operating procedure for the diagnosis and treatment of patients with open fractures exists in their hospital. Only 25 % leave pre-hospitalisation applied dressings intact until arrival of the patient in the operating room, and 40 % make this decision depending on information provided by pre-hospitalisation emergency personnel. 84 % participants exclude the use of antibiotic-coated implants in the treatment of open fractures. The favoured stabilisation method in Gustilo type I fractures is definitive internal osteosynthesis and primary wound closure for 61 % of respondents. In Gustilo type II (74 %) and type III fractures (93 %), temporary external fixation is preferred. High-pressure pulsatile lavage is used by 22 % responding surgeons in Gustilo type I fractures, 53 % for type II fractures and 67 % for type III fractures.

CONCLUSIONS

Open fracture management differs considerably among surgeons in Germany. Further studies are needed to deliver high-quality evidence concerning primary fracture stabilisation, soft tissue management and second-look operations. Existing evidence-based recommendations for general treatment, antibiotic prophylaxis and soft tissue management should be followed more strictly in clinical practice.

摘要

背景

开放性骨折是骨科急症,存在感染、骨不连和软组织并发症的高风险。高质量循证研究的缺乏阻碍了循证治疗。本研究的目的是阐明德国目前开放性骨折的治疗现状,并确定治疗中的主要差异。

方法

要求外科医生完成一份由专家共识制定的包含45项内容的在线问卷。第一部分涵盖开放性骨折治疗的一般原则问题。第二部分包括软组织处理、初始手术固定的首选方法、微生物检测、脉冲冲洗和局部抗生素的使用、抗生素方案、二次探查手术和血液检测等问题。

结果

653名受访者中,364人(65%)完成了在线调查的第一部分,314人(48%)完成了第二部分。55%的人回答说他们医院有开放性骨折患者诊断和治疗的标准操作程序。只有25%的人在患者到达手术室前保持院前应用的敷料完整,40%的人根据院前急救人员提供的信息做出这一决定。84%的参与者在开放性骨折治疗中排除使用抗生素涂层植入物。对于I型Gustilo骨折,61%的受访者首选确定性内固定和一期伤口闭合。在II型(74%)和III型Gustilo骨折(93%)中,首选临时外固定。22%的I型Gustilo骨折受访者、53%的II型骨折受访者和67%的III型骨折受访者使用高压脉冲冲洗。

结论

德国外科医生对开放性骨折的治疗差异很大。需要进一步研究以提供关于骨折初次固定、软组织处理和二次探查手术的高质量证据。临床实践中应更严格遵循现有的关于一般治疗、抗生素预防和软组织处理的循证建议。

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