Rao K R, Patel A R
Department of Medicine, Cook Country Hospital, Chicago, Ill.
South Med J. 1989 Aug;82(8):1034-6. doi: 10.1097/00007611-198908000-00025.
Delayed hemolytic transfusion reaction (DHTR) developed in three patients with sickle cell anemia seen over an 18-month period at Cook Country Hospital. The DHTR was associated with severe pain crisis, with spherocytic hemolytic anemia, a positive direct antiglobulin test result, previously undetected erythrocyte alloantibodies, and disappearance of Hb A on cellulose acetate electrophoresis. Delayed hemolytic transfusion reactions may be more common than is generally recognized and should be considered when a patient has a sickle cell pain crisis shortly after receiving a transfusion.
在库克县医院18个月期间诊治的3例镰状细胞贫血患者中发生了迟发性溶血性输血反应（DHTR）。DHTR与严重疼痛危象、球形红细胞溶血性贫血、直接抗球蛋白试验结果阳性、先前未检测到的红细胞同种抗体以及醋酸纤维素电泳时Hb A消失有关。迟发性溶血性输血反应可能比普遍认为的更为常见，当患者在输血后不久出现镰状细胞疼痛危象时应予以考虑。
