School of Environmental Science and Engineering, Zhejiang Gongshang University, Hangzhou 310012, China.
School of Environmental Science and Engineering, Zhejiang Gongshang University, Hangzhou 310012, China.
Bioresour Technol. 2016 Dec;221:15-25. doi: 10.1016/j.biortech.2016.08.102. Epub 2016 Sep 7.
The effects of Erythromycin (ERY) and oxytetracycline (OTC), including individual and combinative effect, on enhanced biological phosphorus removal (EBPR) system within a short-term (24h) were evaluated in this study. Results showed that the P-removal efficiency decreased to 34.6% and 0.0% under the effect of ERY (10mg/L) and OTC (10mg/L) for 24h. OTC concentration higher than 5mg/L was sufficient to cause serious adverse impact on the EBPR performance. While the performance of EBPR system will be impacted by ERY above 10mg/L. OTC, due to its special antibacterial action to the gram-negative bacteria which most PAOs belong to, has more serious negative effect on the EBPR performance than ERY does. Moreover, in the combined antibiotics test, neither synergistic nor antagonistic effect was detected between ERY and OTC. Finally, ERY (10mg/L) and OTC (10mg/L) could inhibit the microorganisms' activity, while couldn't induce serious microorganisms death within 24h.
本研究评估了红霉素（ERY）和土霉素（OTC），包括单独和联合作用，对短期（24 小时）强化生物除磷（EBPR）系统的影响。结果表明，ERY（10mg/L）和 OTC（10mg/L）作用 24 小时后，磷去除效率分别降至 34.6%和 0.0%。OTC 浓度高于 5mg/L 足以对 EBPR 性能造成严重的不利影响。而 ERY 高于 10mg/L 时，EBPR 系统的性能将受到影响。由于 OTC 对大多数 PAOs 属于的革兰氏阴性菌具有特殊的抗菌作用，因此对 EBPR 性能的负面影响比 ERY 更严重。此外，在联合抗生素试验中，ERY 和 OTC 之间未检测到协同或拮抗作用。最后，ERY（10mg/L）和 OTC（10mg/L）可以抑制微生物的活性，但在 24 小时内不会导致严重的微生物死亡。
