Suppr超能文献

国家精液检测和咨询项目在利比里亚男性埃博拉幸存者中的实施情况-2015-2016 年。

Implementation of a National Semen Testing and Counseling Program for Male Ebola Survivors - Liberia, 2015-2016.

出版信息

MMWR Morb Mortal Wkly Rep. 2016 Sep 16;65(36):963-6. doi: 10.15585/mmwr.mm6536a5.

Abstract

According to World Health Organization (WHO) data, the Ebola virus disease (Ebola) outbreak that began in West Africa in 2014 has resulted in 28,603 cases and 11,301 deaths (1). In March 2015, epidemiologic investigation and genetic sequencing in Liberia implicated sexual transmission from a male Ebola survivor, with Ebola virus detected by reverse transcription-polymerase chain reaction (RT-PCR) 199 days after symptom onset (2,3), far exceeding the 101 days reported from an earlier Ebola outbreak (4). In response, WHO released interim guidelines recommending that all male survivors, in addition to receiving condoms and sexual risk reduction counseling at discharge from an Ebola treatment unit (ETU), be offered semen testing for Ebola virus RNA by RT-PCR 3 months after disease onset, and every month thereafter until two consecutive semen specimens collected at least 1 week apart test negative for Ebola virus RNA (5). Male Ebola survivors should also receive counseling to promote safe sexual practices until their semen twice tests negative. When these recommendations were released, testing of semen was not widely available in Liberia. Challenges in establishing and operating the first nationwide semen testing and counseling program for male Ebola survivors included securing sufficient resources for the program, managing a public health semen testing program in the context of ongoing research studies that were also collecting and screening semen, identification of adequate numbers of trained counselors and appropriate health communication messages for the program, overcoming Ebola survivor-associated stigma, identification and recruitment of male Ebola survivors, and operation of mobile teams.

摘要

根据世界卫生组织(WHO)的数据,2014 年始于西非的埃博拉病毒病(Ebola)疫情已导致 28603 例病例和 11301 人死亡(1)。2015 年 3 月,在利比里亚开展的流行病学调查和基因测序工作提示,病毒可能通过性传播,一名埃博拉幸存者传染给另一名男性,病毒是在症状出现 199 天后通过逆转录聚合酶链反应(RT-PCR)检测到的(2,3),远超此前一次埃博拉疫情中报告的 101 天(4)。对此,世卫组织发布了临时指南,建议所有男性幸存者在离开埃博拉治疗中心(ETU)时除了获得避孕套和性风险降低咨询外,还应在发病后 3 个月接受 RT-PCR 检测埃博拉病毒 RNA 检测,此后每月一次,直到至少相隔 1 周连续两次采集的精液标本检测埃博拉病毒 RNA 均为阴性(5)。男性埃博拉幸存者也应接受咨询,以促进安全性行为,直至两次精液检测均为阴性。这些建议发布时,利比里亚还未广泛开展精液检测。为男性埃博拉幸存者建立和实施全国范围的精液检测和咨询方案所面临的挑战包括为该方案争取充足资源,在开展研究工作的同时管理公共卫生精液检测项目,这些研究也在采集和筛查精液,为该方案确定足够数量的经过培训的咨询员和适当的健康传播信息,克服埃博拉幸存者相关耻辱感,确定和招募男性埃博拉幸存者,以及运行流动小组。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验