植物脂类组学与人类和环境健康。

The plant lipidome in human and environmental health.

机构信息

Michigan State University-U.S. Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA.

Michigan State University-U.S. Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA. Great Lakes Bioenergy Research Center, Michigan State University, East Lansing, MI 48824, USA.

出版信息

Science. 2016 Sep 16;353(6305):1228-32. doi: 10.1126/science.aaf6206.

DOI:10.1126/science.aaf6206

PMID:27634522

Abstract

Lipids and oils derived from plant and algal photosynthesis constitute much of human daily caloric intake and provide the basis for high-energy bioproducts, chemical feedstocks for countless applications, and even fossil fuels over geological time scales. Sustainable production of high-energy compounds from plants is essential to preserving fossil fuel sources and ensuring the well-being of future generations. As a result of progress in basic research on plant and algal lipid metabolism, in combination with advances in synthetic biology, we can now tailor plant lipids for desirable biological, physical, and chemical properties. We highlight recent advances in plant lipid translational biology and discuss untapped areas of research that might expand the application of plant lipids.

摘要

来源于植物和藻类光合作用的脂类和油类构成了人类日常卡路里摄入量的很大一部分，为高能生物制品、无数应用的化学原料，甚至是地质时间尺度上的化石燃料提供了基础。从植物中可持续地生产高能化合物对于保护化石燃料资源和确保后代的福祉至关重要。由于植物和藻类脂类代谢基础研究的进展，结合合成生物学的进步，我们现在可以根据需要定制植物脂类的生物、物理和化学特性。我们重点介绍了植物脂类转化生物学的最新进展，并讨论了可能扩大植物脂类应用的未开发研究领域。