Yuk Jin-Sung
Obstetrics and Gynecology/School of Medicine, MizMedi Hospital, Eulji University , Seoul , Republic of Korea.
PeerJ. 2016 Aug 24;4:e2374. doi: 10.7717/peerj.2374. eCollection 2016.
The aim of this study was to determine the incidence rates of endometrial hyperplasia (EH) and endometrial cancer (EC) in the Republic of Korea using national insurance claim data generated from 2009 to 2012.
Data that were generated from 2009 to 2012 were sourced from the Korean Health Insurance Review and Assessment Service-National Inpatients Sample database. The data from women who were assigned diagnosis codes representing EH or EC within 1 month of being assigned codes that corresponded to procedures that included endometrial biopsies and several types of gynecologic surgeries to obtain endometrial pathology samples, were selected for analysis.
Data from 2,477,424 women were entered into the database between 2009 and 2012, and the data from 1,868 women with EH and 868 women with EC were extracted for analysis. The mean ages of the patients were 44.1 ± 0.4 years for those with EH and 52.7 ± 0.6 years for those with EC. The EH and EC incidence rates were 37 per 100,000 woman-years and 8 per 100,000 woman-years, respectively. The EH and EC incidence rates peaked when the women were in their late forties and fifties, respectively.
The EH and EC incidence rates determined in this study were somewhat lower than those determined from previous studies. Further studies are required that adjust the data for race, menopausal hormone therapy, and obesity.
本研究旨在利用2009年至2012年产生的国民保险理赔数据，确定韩国子宫内膜增生（EH）和子宫内膜癌（EC）的发病率。
2009年至2012年产生的数据来自韩国健康保险审查与评估服务中心-全国住院患者样本数据库。选取在被分配与包括子宫内膜活检及几种妇科手术以获取子宫内膜病理样本的程序相对应的编码后1个月内被分配代表EH或EC的诊断编码的女性的数据进行分析。
2009年至2012年期间，2,477,424名女性的数据被录入数据库，从中提取了1,868名EH患者和868名EC患者的数据进行分析。EH患者的平均年龄为44.1±0.4岁，EC患者的平均年龄为52.7±0.6岁。EH和EC的发病率分别为每100,000女性年37例和每100,000女性年8例。EH和EC的发病率分别在女性接近五十岁和六十岁时达到峰值。
本研究确定的EH和EC发病率略低于先前研究确定的发病率。需要进一步研究对种族、绝经激素治疗和肥胖数据进行调整。
