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[复发性自然流产女性体内体液抗体的发生率及意义]

[Incidence and significance of humoral antibodies in females with recurrent spontaneous abortions].

作者信息

Donat H, Fritzsche C, Morenz J

机构信息

Klinik für Gynäkologie und Geburtshilfe, Klinikbereich I (Landesfrauenklinik), Medizinischen Akademie, Magdeburg.

出版信息

Zentralbl Gynakol. 1989;111(12):811-5.

PMID:2763751
Abstract

Serum samples from 70 patients with two or more early spontaneous abortions and, for comparison, sera from 20 healthy and fertile women were assayed by indirect immunofluorescence for the presence of antibodies to sperms and genital organ antigens and for non-organ specific and organ specific antibodies. All sera were tested for thyreoglobulin antibodies by hemagglutination. The frequency of sperm antibodies and autoantibodies was significantly higher in patients with recurrent abortions than in the control group. There was no relation between the type or titer of antibodies and the clinical data of the patients.

摘要

对70例有两次或更多次早期自然流产的患者的血清样本,以及作为对照的20名健康且可生育女性的血清,通过间接免疫荧光法检测抗精子抗体、生殖器官抗原抗体、非器官特异性抗体和器官特异性抗体的存在情况。所有血清均通过血凝试验检测甲状腺球蛋白抗体。反复流产患者中精子抗体和自身抗体的频率显著高于对照组。抗体类型或滴度与患者的临床数据之间无关联。

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