Szmolenszky T, Márk B, Kiss T, Trombitás K
1st Department of Surgery, Pécs University Medical School, Hungary.
Acta Chir Hung. 1989;30(2):145-55.
The vertical and longitudinal ultrastructural changes of the crural muscle (triceps surae) were studied in a selected patient material of 18 patients suffering from post-thrombotic syndrome. The transmission and scanning electron microscopic method helped in revealing that the damage had affected the contractile system, the mitochondria and the endoplasmic reticulum and in addition marked degenerative phenomena occurred. It was shown that vertically the impairments of the fine structure were localized in foci and involved the muscle layers to the same extent. Longitudinally--distally--the muscle changes displayed an increasingly aggravating diffuse appearance. Of the several factors responsible for the development of the pathological ultrastructural picture, tissue hypoxia and metabolic disorder, as well as a decreased microcirculation (hypoperfusion) and chronic inactivity are to be emphasized.
在选取的18例患有血栓后综合征的患者材料中，研究了小腿肌肉（腓肠肌）的垂直和纵向超微结构变化。透射电子显微镜和扫描电子显微镜方法有助于揭示损伤已影响收缩系统、线粒体和内质网，此外还出现了明显的退行性现象。结果表明，垂直方向上，精细结构的损伤局限于病灶，且对各肌层的影响程度相同。纵向——向远端——肌肉变化呈现出日益加重的弥漫性外观。在导致病理性超微结构图像形成的几个因素中，组织缺氧和代谢紊乱，以及微循环减少（灌注不足）和长期不活动应予以强调。
