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应激性心肌病与栓塞事件

Takotsubo Syndrome and Embolic Events.

作者信息

El-Battrawy Ibrahim, Borggrefe Martin, Akin Ibrahim

机构信息

First Department of Medicine, Medical Faculty Mannheim, University Heidelberg, Theodor-Kutzer-Ufer 1-3, Mannheim 68167, Germany; DZHK (German Center for Cardiovascular Research), Partner Site, Heidelberg-Mannheim, Theodor-Kutzer-Ufer 1-3, Mannheim 68167, Germany.

First Department of Medicine, Medical Faculty Mannheim, University Heidelberg, Theodor-Kutzer-Ufer 1-3, Mannheim 68167, Germany; DZHK (German Center for Cardiovascular Research), Partner Site, Heidelberg-Mannheim, Theodor-Kutzer-Ufer 1-3, Mannheim 68167, Germany.

出版信息

Heart Fail Clin. 2016 Oct;12(4):543-50. doi: 10.1016/j.hfc.2016.06.011. Epub 2016 Jul 30.

Abstract

Takotsubo cardiomyopathy (TTC), initially defined as a benign disease, is associated with several complications. One of them is a thromboembolism, which is clinically presented by events such as stroke, ventricular thrombi, and peripheral embolization, and can be present at index event of TCC as well as at any time in disease course. Patients with elevated C-reactive protein levels, markedly elevated D-dimers and severely impaired left ventricular function seem to be at higher risk of developing thrombemboli. Treatment strategies prescribed in the management of thombembolic complications in patients with acute myocardial infarction includes a short course of anticoagulation. A similar analogy could also be considered for patients with TTC presenting with this complications. Nevertheless, an individualized close-follow-up is of utmost importance to avoid any relapse and not to oversee any impeding complications in light of dynamic processes in myocardial stunning.

摘要

应激性心肌病(TTC)最初被定义为一种良性疾病,它与多种并发症相关。其中之一是血栓栓塞,临床上表现为中风、心室血栓和外周栓塞等事件,在TCC的首发事件时以及疾病过程中的任何时候都可能出现。C反应蛋白水平升高、D - 二聚体显著升高以及左心室功能严重受损的患者似乎发生血栓栓塞的风险更高。急性心肌梗死患者血栓栓塞并发症管理中规定的治疗策略包括短期抗凝。对于出现这种并发症的TTC患者也可考虑类似的方法。然而,鉴于心肌顿抑的动态过程,个体化的密切随访对于避免任何复发以及不忽视任何潜在并发症至关重要。

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