von Brevern M, Lempert T
Department of Neurology, Park-Klinik Weissensee and Vestibular Research Group, Berlin, Germany.
Department of Neurology, Schlosspark-Klinik and Vestibular Research Group, Berlin, Germany.
Handb Clin Neurol. 2016;137:301-16. doi: 10.1016/B978-0-444-63437-5.00022-4.
During the last decades a new vestibular syndrome has emerged that is now termed vestibular migraine (VM). The main body of evidence for VM is provided by epidemiologic data demonstrating a strong association between migraine and vestibular symptoms. Today, VM is recognized as one of the most common causes of episodic vertigo. The clinical presentation of VM is heterogeneous in terms of vestibular symptoms, duration of episodes, and association with migrainous accompaniments. Similar to migraine, there is no clinical or laboratory confirmation for VM and the diagnosis relies on the history and the exclusion of other disorders. Recently, diagnostic criteria for VM have been elaborated jointly by the International Headache Society and the Bárány Society. Clinical examination of patients with acute VM has clarified that the vast majority of patients with VM suffer from central vestibular dysfunction. Findings in the interval may yield mild signs of damage to both the central vestibular and ocular motor system and to the inner ear. These interictal clinical signs are not specific to VM but can be also observed in migraineurs without a history of vestibular symptoms. How migraine affects the vestibular system is still a matter of speculation. In the absence of high-quality therapeutic trials, treatment is targeted at the underlying migraine.
在过去几十年里,一种新的前庭综合征出现了,现在被称为前庭性偏头痛(VM)。VM的主要证据来自流行病学数据,这些数据表明偏头痛与前庭症状之间存在很强的关联。如今,VM被认为是发作性眩晕最常见的原因之一。VM的临床表现在前庭症状、发作持续时间以及与偏头痛伴随症状的关联方面存在异质性。与偏头痛类似,VM没有临床或实验室确诊方法,诊断依赖于病史以及排除其他疾病。最近,国际头痛协会和巴兰尼协会联合制定了VM的诊断标准。对急性VM患者的临床检查表明,绝大多数VM患者存在中枢前庭功能障碍。发作间期的检查结果可能显示中枢前庭和眼动系统以及内耳有轻度损伤迹象。这些发作间期的临床体征并非VM所特有,在没有前庭症状病史的偏头痛患者中也可能观察到。偏头痛如何影响前庭系统仍是一个推测的问题。在缺乏高质量治疗试验的情况下,治疗针对的是潜在的偏头痛。