Zhou L L, Wang W Z, Yang Y C, Zhuang J H
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 Dec;30(24):1983-1986. doi: 10.13201/j.issn.1001-1781.2016.24.024.
Pathogenesis, clinical characteristics and treatments of vestibular migraine(VM) in recent years were retrospectively analyzed. The results showed that VM had diversified vestibular symptoms. VM may show a mild central and peripheral vestibular dysfunction during ictal and interictal period. Although no specificity, it could provide important references to identify VM. The pathogenesis of VM, which depended upon the clues of migraine, had been supposed to be probably related to genetic susceptibility, neurotransmitter changes induced by trigeminal nerve, and abnormal integration of central signal, and further exploration of functional abnormalities in brain-related areas showed by functional imaging technology may shed light on the pathogenesis of VM. Until now, the pharmacotherapies of VM have been still based on the treatment of migraine and the efficacy remains to be clarified.
回顾性分析近年来前庭性偏头痛（VM）的发病机制、临床特征及治疗方法。结果显示，VM具有多样化的前庭症状。VM在发作期和发作间期可能表现为轻度的中枢性和外周性前庭功能障碍。虽无特异性，但可为VM的识别提供重要参考。VM的发病机制推测可能与偏头痛线索有关，可能与遗传易感性、三叉神经诱导的神经递质变化以及中枢信号的异常整合有关，而通过功能成像技术进一步探索脑相关区域显示的功能异常可能有助于揭示VM的发病机制。目前，VM的药物治疗仍基于偏头痛的治疗，其疗效尚待明确。
